海马体积作为老年抑郁症患者短期ECT预后的预测因子

IF 4.4 2区医学 Q1 GERIATRICS & GERONTOLOGY

American Journal of Geriatric Psychiatry Pub Date : 2005-10-01 DOI:10.1097/00019442-200510000-00011

Ruby E. Lekwauwa B.S., Douglas R. McQuoid B.S., David C. Steffens M.D., M.H.S.

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引用次数: 17

摘要

目的探讨海马体积与急性电休克治疗(ECT)疗效的关系。方法采用Montgomery-Asberg抑郁评定量表(MADRS)评定抑郁程度，采用磁共振成像(mri)评估海马体积。结果在控制基线MADRS评分后，ECT指数疗程后，较大的右海马体积与较高的MADRS评分相关。结论这些结果与一项评估海马体积与药物治疗关系的研究结果相反。研究结果表明，需要在这一领域进行进一步的研究。

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Hippocampal Volume as a Predictor of Short-Term ECT Outcomes in Older Patients With Depression

Objective

The authors examined the relationship between hippocampal volume and acute electroconvulsive therapy (ECT) outcomes.

Methods

Depression was measured by Montgomery-Asberg Depression Rating Scale (MADRS) scores, and hippocampal volume was assessed by magnetic resonance imaging.

Results

After controlling for baseline MADRS score, larger right-hippocampal volume was associated with higher MADRS scores after an index course of ECT.

Conclusion

These results are the converse of those obtained in a study assessing the relationship between hippocampal volume and pharmacotherapy. The findings suggest a need for further study in this area.

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来源期刊

American Journal of Geriatric Psychiatry 医学-精神病学

CiteScore

13.00

自引率

4.20%

发文量

381

审稿时长

26 days

期刊介绍： The American Journal of Geriatric Psychiatry is the leading source of information in the rapidly evolving field of geriatric psychiatry. This esteemed journal features peer-reviewed articles covering topics such as the diagnosis and classification of psychiatric disorders in older adults, epidemiological and biological correlates of mental health in the elderly, and psychopharmacology and other somatic treatments. Published twelve times a year, the journal serves as an authoritative resource for professionals in the field.