{"title":"红细胞贮藏损伤的分子机制","authors":"William C. Horne PhD","doi":"10.1016/0278-6222(88)90002-2","DOIUrl":null,"url":null,"abstract":"<div><p>Preserved erythrocytes undergo several changes during storage, collectively referred to as the storage lesion, which reduce the effectiveness of stored erythrocytes following transfusion. This review describes the mechanisms leading to these changes, so far as they are known, and discusses the relationship of the changes to one another and how they contribute to the diminished function of stored erythrocytes.</p></div>","PeriodicalId":101030,"journal":{"name":"Plasma Therapy and Transfusion Technology","volume":"9 3","pages":"Pages 259-273"},"PeriodicalIF":0.0000,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0278-6222(88)90002-2","citationCount":"6","resultStr":"{\"title\":\"Molecular mechanisms of the red cell storage lesion\",\"authors\":\"William C. Horne PhD\",\"doi\":\"10.1016/0278-6222(88)90002-2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Preserved erythrocytes undergo several changes during storage, collectively referred to as the storage lesion, which reduce the effectiveness of stored erythrocytes following transfusion. This review describes the mechanisms leading to these changes, so far as they are known, and discusses the relationship of the changes to one another and how they contribute to the diminished function of stored erythrocytes.</p></div>\",\"PeriodicalId\":101030,\"journal\":{\"name\":\"Plasma Therapy and Transfusion Technology\",\"volume\":\"9 3\",\"pages\":\"Pages 259-273\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1988-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/0278-6222(88)90002-2\",\"citationCount\":\"6\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Plasma Therapy and Transfusion Technology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/0278622288900022\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Plasma Therapy and Transfusion Technology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0278622288900022","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Molecular mechanisms of the red cell storage lesion
Preserved erythrocytes undergo several changes during storage, collectively referred to as the storage lesion, which reduce the effectiveness of stored erythrocytes following transfusion. This review describes the mechanisms leading to these changes, so far as they are known, and discusses the relationship of the changes to one another and how they contribute to the diminished function of stored erythrocytes.