对同时被诊断患有慢性偏头痛和颞下颌关节紊乱症的患者使用A型肉毒毒素的效果:回顾性病例系列。

IF 8.1 1区 物理与天体物理 Q1 PHYSICS, MULTIDISCIPLINARY
Physical review letters Pub Date : 2024-11-01 Epub Date: 2022-03-14 DOI:10.1080/08869634.2022.2045114
Andrew J Gross, John W Hudson, Catalina Matias, Brady J Jones
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引用次数: 0

摘要

目的:伴有颞下颌关节紊乱(TMD)的慢性偏头痛(CME)是一种严重的疾病,但有效的治疗方法有限。本研究探讨了在颞下颌关节镜手术的基础上使用鬼臼毒素 A(BtxA)作为辅助疗法对缓解 CME 的有效性:方法:对接受颞下颌关节镜检查并注射或不注射 BtxA 治疗 CME 的患者进行回顾性队列研究。评估变量包括疼痛(使用视觉模拟量表(VAS))、最大切口开度(MIO)、肌肉酸痛、头痛频率和持续时间:符合纳入标准的 60 名患者(44 名 BtxA 患者,16 名对照组患者)中有 56 名女性(93.3%)。据报告,接受 BtxA 治疗的患者疼痛明显减轻(p p 结论:这些结果支持使用 BtxA 作为辅助治疗:这些结果支持将 BtxA 治疗与关节镜手术相结合,用于治疗 TMD 下的 CME。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effects of onabotulinumtoxin A in patients concurrently diagnosed with chronic migraine encephalalgia and temporomandibular disorders: A retrospective case series.

Objective: Chronic migraine encephalalgia (CME) with concomitant temporomandibular disorder (TMD) is a serious illness with limited effective treatment options. This study explores the effectiveness of onabotulinumtoxinA (BtxA) as an adjunct therapeutic to TMJ arthroscopy in the relief of CME.

Methods: A retrospective cohort study of patients receiving TMJ arthroscopy, with or without BtxA injections for CME, was conducted. Variables assessed include pain using a visual analog scale (VAS), maximal incisal opening (MIO), muscle soreness, and headache frequency and duration.

Results: Sixty patients (44 BtxA, 16 Control), consisting of 56 (93.3%) females, met inclusion criteria. A significant reduction in pain is reported with patients receiving BtxA (p < 0.0001) on VAS as compared to Control group. BtxA treatment also significantly reduced headache frequency and duration (p < 0.05).

Conclusion: These results support the use of adjunctive BtxA treatment with arthroscopy for the treatment of CME in the context of TMD.

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来源期刊
Physical review letters
Physical review letters 物理-物理:综合
CiteScore
16.50
自引率
7.00%
发文量
2673
审稿时长
2.2 months
期刊介绍: Physical review letters(PRL)covers the full range of applied, fundamental, and interdisciplinary physics research topics: General physics, including statistical and quantum mechanics and quantum information Gravitation, astrophysics, and cosmology Elementary particles and fields Nuclear physics Atomic, molecular, and optical physics Nonlinear dynamics, fluid dynamics, and classical optics Plasma and beam physics Condensed matter and materials physics Polymers, soft matter, biological, climate and interdisciplinary physics, including networks
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