纳米聚合物GluLa-DPG-PEG600-F可穿透细胞并在大鼠体内沉积

Naukovii visnik Skhidnoievropeis''kogo natsional''nogo universitetu imeni Lesi Ukrayinki Seriia Biologichni nauki Pub Date : 2019-01-26 DOI:10.29038/2617-4723-2016-337-12-138-142

B. Chekh, M. Ferens, N. Susol, S. Varvarenko, D. Ostapiv, V. Vlizlo

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引用次数: 2

摘要

通过荧光显微镜观察，我们发现纳米聚合物GluLa-DPG-PEG600-F可以通过结合膜穿透牛精子细胞，并通过结合蛋白沉积在肌肉组织的注射剂中。纳米聚合物对精子细胞代谢活性的影响降低了氧气摄入和氧化还原活性。我们还测定了高剂量纳米聚合物添加到精子中的精子细胞存活时间。

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Nanopolymer GluLa-DPG-PEG600-F Can Penetrate into Cells and Deposite in Rats Body

Via fluorescence microscopy we found that nanopolymer GluLa-DPG-PEG600-F can penetrate bovine sperm cells via binding membranes and deposit in the cite of injection in muscle tissues by binding proteins.Nanopolymer influences on sperm cells metabolic activity decreases oxygen intake and redox activity. We also determined sperm cell survival time, that was decreased of high doses of nanopolymer added to sperm.

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Naukovii visnik Skhidnoievropeis''kogo natsional''nogo universitetu imeni Lesi Ukrayinki Seriia Biologichni nauki

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审稿时长

15 weeks