Ca2+/CaM 与电压门控 Na+ 通道的相互作用

IF 0.6 Q4 CRIMINOLOGY & PENOLOGY
Safer Communities Pub Date : 2019-12-26 Epub Date: 2019-12-03 DOI:10.1073/pnas.1909835116
Geoffrey S Pitt, Seok-Yong Lee
{"title":"Ca2+/CaM 与电压门控 Na+ 通道的相互作用","authors":"Geoffrey S Pitt, Seok-Yong Lee","doi":"10.1073/pnas.1909835116","DOIUrl":null,"url":null,"abstract":"","PeriodicalId":43879,"journal":{"name":"Safer Communities","volume":"7 1","pages":"26150-26151"},"PeriodicalIF":0.6000,"publicationDate":"2019-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936364/pdf/","citationCount":"0","resultStr":"{\"title\":\"Ca<sup>2+</sup>/CaM interaction with voltage-gated Na<sup>+</sup> channels.\",\"authors\":\"Geoffrey S Pitt, Seok-Yong Lee\",\"doi\":\"10.1073/pnas.1909835116\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\",\"PeriodicalId\":43879,\"journal\":{\"name\":\"Safer Communities\",\"volume\":\"7 1\",\"pages\":\"26150-26151\"},\"PeriodicalIF\":0.6000,\"publicationDate\":\"2019-12-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936364/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Safer Communities\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1073/pnas.1909835116\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2019/12/3 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q4\",\"JCRName\":\"CRIMINOLOGY & PENOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Safer Communities","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1073/pnas.1909835116","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2019/12/3 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"CRIMINOLOGY & PENOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

Gardill等人(1)描述了Ca2+负载钙调蛋白(CaM)和心脏NaV1.5 Na+通道胞内C端(C端结构域[CTD])复合物的晶体结构(Protein Data Bank [PDB]: 6MUD)。他们发现,正如我们报道的(2),NaVCTD, Ca2+-CaM和成纤维细胞生长因子同源因子(FHF) FGF13B(3,4)的三重复合物(PDB: 4JQ0和4JPZ), Ca2+仅占据CaM n -叶,而CaM c -叶采用半开放的构象,当apoCaM结合靶肽时发现(5)。然而,Gardill等人指出,我们已经将我们的结构解释为Ca2+结合到…[③][1]。电子邮件:geoffrey.pitt在}{med.cornell.edu。[1]: # xref-corresp-1-1
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Ca2+/CaM interaction with voltage-gated Na+ channels.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Safer Communities
Safer Communities CRIMINOLOGY & PENOLOGY-
CiteScore
1.60
自引率
0.00%
发文量
18
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信