The value of endosonographic criteria of lymph nodes in the differential diagnosis of the mediastinal lymphadenopathy

The results of a prospective study. Introduction: morphological diagnosis of lymphadenopathy of the mediastinum by aspiration biopsy data presents known difficulties. The search for specific endosonographic patterns for the diagnosis of mediastinal lymph node pathology is relevant. Objective: to study the role of endosonographic patterns in the differential diagnosis of the mediastinal lymphadenopathy. Material and methods: prospective non-randomized one-center. Duration of the study: 01/01/2017 - 12/31/2017. Inclusion criteria: patients with lymphadenopathy of the mediastinum, age over 18 years, the absence of any verified cancer and tuberculosis in history, the patient’s consent to the inclusion. Exclusion criteria: the presence of contraindications to general anesthesia, the refusal to conduct the study. In accordance with the inclusion criteria, 29 patients were enrolled in the study, who underwent endobronchial sonography with subsequent analysis of endosonographic scans by the modified scheme Lei Wang, 2015. Results: as a result of statistical analysis, none of the analyzed factors had a significant effect on the form of the pathological lymphatic lesion, or on the result of the biopsy. The factor: Form p=0,249, Edges - 0,009, Echogenicity - 0,567, Presence of central structure - 0,265, Necrosis sign - 0,326, The presence of the vessel - 0,198, Calcification - 0,612, Matting - 0,368, Vascular patterns - 0,399. Edge: Pearson Correlation -0.248. Conclusion: the use of endosonographic patterns for the differential diagnosis of mediastinal lymphadenopathy and the refusal to perform a biopsy in these patients is currently not possible.