Primary central nervous system lymphoma misdiagnosed as convexity meningioma: A case report

We are reporting the case of a 56-year-old female patient who presented with headache, nausea, and vomiting. Magnetic resonance imaging (MRI) revealed a homogeneous enhancing mass on the left frontal lobe. Based on the impression of a convexity meningioma, surgical treatment was planned, and intravenous (IV) steroids were administered to alleviate brain edema. Additional brain MRI was performed just before surgery for intraoperative navigation, which showed a significant reduction in tumor size. Due to the good response to IV steroids, we suspected that the tumor might be a differ-ent lesion rather than a meningioma, and thus, we proceeded with surgery for histologic diagnosis. Intraoperative findings revealed a whitish-gray, rubbery tumor adhering to the dura and arachnoid membrane, which was removed, and intraoperative frozen biopsy reported lymphoma. Finally, the patient was diagnosed with diffuse large B-cell lymphoma. This case report highlights the impor-tance of considering lesions that may be responsive to steroids and the imaging characteristics of lymphoma, which can be distinguished from other lesions.