Annemarie Pielaat, Angelina Kuijpers, Ellen Delfgou-van Asch, Wilfrid van Pelt, Lucas Wijnands
{"title":"35种肠沙门氏菌血清型的表型行为与流行病学和基因组数据的比较","authors":"Annemarie Pielaat, Angelina Kuijpers, Ellen Delfgou-van Asch, Wilfrid van Pelt, Lucas Wijnands","doi":"10.1016/j.profoo.2016.02.085","DOIUrl":null,"url":null,"abstract":"<div><p>The behavior of 35 different <em>Salmonella enterica</em> serovars was investigated in an <em>in vitro</em> gastro-intestinal tract (GIT) system. Virulence was expressed as the probability of infection, P(inf), i.e. fraction of the ON-culture invading into Caco-2 cells after GIT passage. Results show that the (average) P(inf) of <em>Salmonella</em> serovars ranges from 1.7 10<sup>-8</sup> (<em>S.</em>Kedougou) to 5.3 10<sup>-5</sup> (<em>S.</em>Typhimurium). In general, the P(inf) corresponds to available epidemiological and virulotypic data from literature. Still, individual exceptions exist and it is hypothesized that the public health risk from <em>Salmonella</em> is associated with exposure (prevalence, dose and/or acquired immunity) rather than difference in virulence.</p></div>","PeriodicalId":20478,"journal":{"name":"Procedia food science","volume":"7 ","pages":"Pages 53-58"},"PeriodicalIF":0.0000,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.profoo.2016.02.085","citationCount":"5","resultStr":"{\"title\":\"Phenotypic Behavior of 35 Salmonella Enterica Serovars Compared to Epidemiological and Genomic Data\",\"authors\":\"Annemarie Pielaat, Angelina Kuijpers, Ellen Delfgou-van Asch, Wilfrid van Pelt, Lucas Wijnands\",\"doi\":\"10.1016/j.profoo.2016.02.085\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>The behavior of 35 different <em>Salmonella enterica</em> serovars was investigated in an <em>in vitro</em> gastro-intestinal tract (GIT) system. Virulence was expressed as the probability of infection, P(inf), i.e. fraction of the ON-culture invading into Caco-2 cells after GIT passage. Results show that the (average) P(inf) of <em>Salmonella</em> serovars ranges from 1.7 10<sup>-8</sup> (<em>S.</em>Kedougou) to 5.3 10<sup>-5</sup> (<em>S.</em>Typhimurium). In general, the P(inf) corresponds to available epidemiological and virulotypic data from literature. Still, individual exceptions exist and it is hypothesized that the public health risk from <em>Salmonella</em> is associated with exposure (prevalence, dose and/or acquired immunity) rather than difference in virulence.</p></div>\",\"PeriodicalId\":20478,\"journal\":{\"name\":\"Procedia food science\",\"volume\":\"7 \",\"pages\":\"Pages 53-58\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.profoo.2016.02.085\",\"citationCount\":\"5\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Procedia food science\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2211601X16000869\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Procedia food science","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2211601X16000869","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Phenotypic Behavior of 35 Salmonella Enterica Serovars Compared to Epidemiological and Genomic Data
The behavior of 35 different Salmonella enterica serovars was investigated in an in vitro gastro-intestinal tract (GIT) system. Virulence was expressed as the probability of infection, P(inf), i.e. fraction of the ON-culture invading into Caco-2 cells after GIT passage. Results show that the (average) P(inf) of Salmonella serovars ranges from 1.7 10-8 (S.Kedougou) to 5.3 10-5 (S.Typhimurium). In general, the P(inf) corresponds to available epidemiological and virulotypic data from literature. Still, individual exceptions exist and it is hypothesized that the public health risk from Salmonella is associated with exposure (prevalence, dose and/or acquired immunity) rather than difference in virulence.
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