尼日利亚Ondo州接受抗逆转录病毒治疗的艾滋病毒阳性成人高血压患病率和危险因素

IF 0.3 Q4 INFECTIOUS DISEASES
O S Ilesanmi, O. Akpa
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引用次数: 2

摘要

在接受抗逆转录病毒治疗(ART)的人类免疫缺陷病毒/获得性免疫缺陷综合征(PLWHA)患者中,高血压的发生率正在增加。在尼日利亚,全国人类免疫缺陷病毒(艾滋病毒)流行率为1.4%,估计有70万艾滋病感染者正在接受抗逆转录病毒治疗。我们调查了在Ondo州的Owo接受抗逆转录病毒治疗的成年人中高血压患病率和相关因素。材料和方法:对奥沃联邦医疗中心300名艾滋病感染者进行抗逆转录病毒治疗的回顾性研究。高血压定义为收缩压(SBP)≥140 mm Hg和/或舒张压(DBP)≥90 mm Hg。卡方检验用于确定社会人口学/临床参数与高血压之间的关系。采用优势比和校正优势比检查高血压相关危险因素。结果:PLWHA患者平均年龄38.3岁(SD, 10.4),男性占33.7%。抗逆转录病毒治疗的中位持续时间为6年(范围0.5-15年)。高血压患病率为20.3%,其中男性为25.7%,女性为17.5%。开始抗逆转录病毒治疗前高血压患病率为14.7%,开始抗逆转录病毒治疗后高血压患病率为20.3% (p = 0.043)。使用ART前平均收缩压为110±16 mm Hg,使用ART后平均收缩压为118±18 mm Hg (p < 0.001)。开始抗逆转录病毒治疗前的高血压与38岁及以上年龄相关(OR: 2.7;95% ci: 1.3-6.8)。在PLWHA患者中,开始治疗后的高血压与既往高血压相关(AOR: 9.2;95% ci: 4.5-18.6)。结论:HIV治疗方案应包括高血压的筛查和管理。筛查和评估风险因素的对象是在开始抗逆转录病毒治疗前被诊断为高血压的艾滋病感染者,同时在随后的就诊中评估常规血压检查。艾滋病Rev 2020;[j] .中国科学:地球科学
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence and risk factors of hypertension in HIV-positive adults on antiretroviral therapy in Ondo State, Nigeria
Introduction: The occurrence of hypertension in people living with human immunodeficiency virus/ acquired immunodeficiency syndrome (PLWHA) on antiretroviral therapy (ART) is increasing. In Nigeria, where the national human immunodeficiency virus (HIV) prevalence is 1.4%, an estimated 700,000 PLWHA are on ART. We investigated the prevalence of hypertension and associated factors among adults on ART in Owo, Ondo State. Material and methods: A retrospective study with 300 PLWHA on ART in Federal Medical Centre, Owo, was conducted. Hypertension was defined as systolic blood pressure (SBP) ≥ 140 mm Hg and/or diastolic blood pressure (DBP) ≥ 90 mm Hg. Descriptive statistics were performed. Chi-square tests were used to identify associations between sociodemographic/clinical parameters and hypertension. Odds ratio and adjusted odds ratio were used to examine risk factors associated with hypertension. Results: The mean age of PLWHA was 38.3 years (SD, 10.4) and 33.7% were males. Median duration on ART was 6 years (range, 0.5-15). The prevalence of hypertension was 20.3%, with 25.7% in males and 17.5% among females. The prevalence of hypertension before commencing ART was 14.7% and 20.3% after ART was commenced (p = 0.043). Mean SBP was 110 ± 16 mm Hg before ART use and 118 ± 18 after utilization of ART (p < 0.001). Hypertension before commencing ART was associated with age of 38 years and above (OR: 2.7; 95% CI: 1.3-6.8). Amongst PLWHA, hypertension after commencing treatment was associated with being previously hypertensive (AOR: 9.2; 95% CI: 4.5-18.6). Conclusions: HIV treatment programs should include screening and management of hypertension. Screening and assessment of risk factors were directed at PLWHA diagnosed with hypertension before commencing ART, while routine check of blood pressure was evaluated at subsequent visits. HIV AIDS Rev 2020; 19, 3: 199-205 DOI: https://doi.org/10.5114/hivar.2020.99681
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来源期刊
HIV & AIDS Review
HIV & AIDS Review INFECTIOUS DISEASES-
CiteScore
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