胆道闭锁手术治疗的研究进展

Q4 Medicine

中华小儿外科杂志 Pub Date : 2020-03-15 DOI:10.3760/CMA.J.ISSN.0253-3006.2020.03.019

Min Du, S. Zheng

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引用次数: 0

摘要

胆道闭锁(BA)是一种严重危及生命的儿童肝胆疾病。Kasai门肠造口术是BA的一线治疗方法。约60%的BA患者出现胆管炎、肠梗阻、吻合口狭窄、胆漏、胃肠道出血等术后并发症。其中约一半在2-5年内发展为肝硬化和肝功能衰竭，通常需要肝移植。Kasai门肠造口术序贯联合肝移植可显著改善预后。本文从手术年龄、手术技术、腹内/腹外开腹手术、微创与开放式开腹手术、重做开腹手术、肝移植等方面综述了国内外对BA手术治疗的最新研究进展。关键词:胆道闭锁;操作;肝移植

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Recent advances in the researches of surgical treatments for biliary atresia

Biliary atresia (BA) is a severe life-threatening pediatric hepatobiliary condition. Kasai portoenterostomy acts as a first-line treatment for BA. Around 60% of BA patients develop such postoperative complications as cholangitis, intestinal obstruction, anastomotic stricture, bile leakage and gastrointestinal bleeding, etc. And around one half of them develop cirrhosis and liver failure within 2-5 years and liver transplantation is often required. Sequential combination of Kasai portoenterostomy and liver transplantation significantly improves the prognosis. This review summarized the latest domestic and international researches of surgical treatments for BA from the perspectives of operative age, surgical techniques, intra/extra-abdominal Kasai, mini-invasive versus open Kasai, redo Kasai and liver transplantation, etc. Key words: Biliary atresia; Operation; Liver transplantation

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来源期刊

中华小儿外科杂志 Medicine-Pediatrics, Perinatology and Child Health

CiteScore

0.40

自引率

0.00%

发文量

8707

期刊介绍： Chinese Journal of Pediatric Surgery is an academic journal sponsored by the Chinese Medical Association. It mainly publishes original research papers, reviews and comments in this field. The journal was founded in 1980 and is included in well-known databases such as Peking University Journal (Chinese Journal of Humanities and Social Sciences) and CSCD Chinese Science Citation Database Source Journal (including extended version). It is one of the national key academic journals under the supervision of the China Association for Science and Technology. Chinese Journal of Pediatric Surgery enjoys a high reputation and influence in the academic community. The articles published in this journal have a high academic level and practical value, providing readers with a large number of practical cases and industry information, and have received widespread attention and citations from readers.