{"title":"基于纳米药物的同步辐射抗癌靶向和治疗的镅纳米粒子给药系统","authors":"A. Heidari, K. Schmitt, M. Henderson, E. Besana","doi":"10.15761/DOMR.1000343","DOIUrl":null,"url":null,"abstract":"In the current study, thermoplasmonic characteristics of Americium nanoparticles with spherical, core-shell and rod shapes are investigated. In order, to investigate these characteristics, interaction of synchrotron radiation emission as a function of the beam energy and Americium nanoparticles were simulated using 3D finite element method. Firstly, absorption and extinction cross sections were calculated. Then, increases in temperature due to synchrotron radiation emission as a function of the beam energy absorption were calculated in Americium nanoparticles by solving heat equation. The obtained results show that Americium nanorods are more appropriate option for using in optothermal human cancer cells, tissues and tumors treatment method.","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"52 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"12","resultStr":"{\"title\":\"Nanomedicines based americium nanoparticles drug delivery systems for anti-cancer targeting and treatment under synchrotron radiation\",\"authors\":\"A. Heidari, K. Schmitt, M. Henderson, E. Besana\",\"doi\":\"10.15761/DOMR.1000343\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In the current study, thermoplasmonic characteristics of Americium nanoparticles with spherical, core-shell and rod shapes are investigated. In order, to investigate these characteristics, interaction of synchrotron radiation emission as a function of the beam energy and Americium nanoparticles were simulated using 3D finite element method. Firstly, absorption and extinction cross sections were calculated. Then, increases in temperature due to synchrotron radiation emission as a function of the beam energy absorption were calculated in Americium nanoparticles by solving heat equation. The obtained results show that Americium nanorods are more appropriate option for using in optothermal human cancer cells, tissues and tumors treatment method.\",\"PeriodicalId\":10996,\"journal\":{\"name\":\"Dental, Oral and Maxillofacial Research\",\"volume\":\"52 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"12\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Dental, Oral and Maxillofacial Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15761/DOMR.1000343\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Dental, Oral and Maxillofacial Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15761/DOMR.1000343","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Nanomedicines based americium nanoparticles drug delivery systems for anti-cancer targeting and treatment under synchrotron radiation
In the current study, thermoplasmonic characteristics of Americium nanoparticles with spherical, core-shell and rod shapes are investigated. In order, to investigate these characteristics, interaction of synchrotron radiation emission as a function of the beam energy and Americium nanoparticles were simulated using 3D finite element method. Firstly, absorption and extinction cross sections were calculated. Then, increases in temperature due to synchrotron radiation emission as a function of the beam energy absorption were calculated in Americium nanoparticles by solving heat equation. The obtained results show that Americium nanorods are more appropriate option for using in optothermal human cancer cells, tissues and tumors treatment method.