基于纳米药物的同步辐射抗癌靶向和治疗的镅纳米粒子给药系统

A. Heidari, K. Schmitt, M. Henderson, E. Besana
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引用次数: 12

摘要

本文研究了球形、核壳和棒状镅纳米粒子的热等离子体特性。为了研究这些特性,采用三维有限元方法模拟了同步辐射发射作为光束能量的函数与镅纳米粒子的相互作用。首先计算了吸收和消光截面。然后,通过求解热方程,计算了同步辐射发射引起的温度升高与光束能量吸收的关系。所获得的结果表明,镅纳米棒是一种更适合用于光热人体癌细胞、组织和肿瘤治疗的方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Nanomedicines based americium nanoparticles drug delivery systems for anti-cancer targeting and treatment under synchrotron radiation
In the current study, thermoplasmonic characteristics of Americium nanoparticles with spherical, core-shell and rod shapes are investigated. In order, to investigate these characteristics, interaction of synchrotron radiation emission as a function of the beam energy and Americium nanoparticles were simulated using 3D finite element method. Firstly, absorption and extinction cross sections were calculated. Then, increases in temperature due to synchrotron radiation emission as a function of the beam energy absorption were calculated in Americium nanoparticles by solving heat equation. The obtained results show that Americium nanorods are more appropriate option for using in optothermal human cancer cells, tissues and tumors treatment method.
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