{"title":"外伤性溃疡性肉芽肿伴间质嗜酸性粒细胞增多:附4例文献复习","authors":"S. Mehta, Rajeshwari K Muthusamy","doi":"10.3126/jpn.v10i2.24596","DOIUrl":null,"url":null,"abstract":"A series of four cases of Traumatic Ulcerative Granuloma with Stromal Eosinophilia in the lateral borders of the tongue were analyzed regarding oral hygiene, sharp tooth, clinical presentation, histology, and follow-up. The lesion manifests as a small solitary ulcer with induration in the oral mucosa mimicking malignancy. Histology revealed ulcers with exudate and granulation tissue with dense polymorphous infiltrate rich in eosinophils. Infiltrate extends down in between the skeletal muscle fibers and salivary gland lobules. A sharp tooth was found to be the inciting factor in a proportion of cases. Histopathological examination is mandatory to confirm the diagnosis and to exclude malignancy and other eosinophil rich disorders. ABSTRACT Sangita Sharma Mehta1, Rajeshwari K Muthusamy1","PeriodicalId":31517,"journal":{"name":"Journal of Pathology of Nepal","volume":"49 1","pages":"1779-1782"},"PeriodicalIF":0.0000,"publicationDate":"2020-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Traumatic ulcerative granuloma with stromal eosinophilia: a series of four cases with review of literature\",\"authors\":\"S. Mehta, Rajeshwari K Muthusamy\",\"doi\":\"10.3126/jpn.v10i2.24596\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A series of four cases of Traumatic Ulcerative Granuloma with Stromal Eosinophilia in the lateral borders of the tongue were analyzed regarding oral hygiene, sharp tooth, clinical presentation, histology, and follow-up. The lesion manifests as a small solitary ulcer with induration in the oral mucosa mimicking malignancy. Histology revealed ulcers with exudate and granulation tissue with dense polymorphous infiltrate rich in eosinophils. Infiltrate extends down in between the skeletal muscle fibers and salivary gland lobules. A sharp tooth was found to be the inciting factor in a proportion of cases. Histopathological examination is mandatory to confirm the diagnosis and to exclude malignancy and other eosinophil rich disorders. ABSTRACT Sangita Sharma Mehta1, Rajeshwari K Muthusamy1\",\"PeriodicalId\":31517,\"journal\":{\"name\":\"Journal of Pathology of Nepal\",\"volume\":\"49 1\",\"pages\":\"1779-1782\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-09-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Pathology of Nepal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3126/jpn.v10i2.24596\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Pathology of Nepal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3126/jpn.v10i2.24596","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
本文对4例外伤性溃疡性肉芽肿伴舌侧缘间质嗜酸性粒细胞增多的病例进行口腔卫生、尖牙、临床表现、组织学及随访等方面的分析。病变表现为口腔黏膜小的单发溃疡伴硬化,形似恶性肿瘤。组织学显示溃疡有渗出物和肉芽组织,密集的多形性浸润,富含嗜酸性粒细胞。浸润向下延伸至骨骼肌纤维和唾液腺小叶之间。在一定比例的病例中,锋利的牙齿被发现是诱发因素。组织病理学检查是必要的,以确认诊断和排除恶性肿瘤和其他嗜酸性粒细胞丰富的疾病。Sangita Sharma Mehta1, Rajeshwari K Muthusamy1
Traumatic ulcerative granuloma with stromal eosinophilia: a series of four cases with review of literature
A series of four cases of Traumatic Ulcerative Granuloma with Stromal Eosinophilia in the lateral borders of the tongue were analyzed regarding oral hygiene, sharp tooth, clinical presentation, histology, and follow-up. The lesion manifests as a small solitary ulcer with induration in the oral mucosa mimicking malignancy. Histology revealed ulcers with exudate and granulation tissue with dense polymorphous infiltrate rich in eosinophils. Infiltrate extends down in between the skeletal muscle fibers and salivary gland lobules. A sharp tooth was found to be the inciting factor in a proportion of cases. Histopathological examination is mandatory to confirm the diagnosis and to exclude malignancy and other eosinophil rich disorders. ABSTRACT Sangita Sharma Mehta1, Rajeshwari K Muthusamy1