多囊卵巢综合征患者的血浆皮质醇水平在晚上高于早上。

M. Kiałka, Agnieszka Ociepka, T. Milewicz, M. Krzyczkowska-Sendrakowska, Katarzyna Gosztyła, E. Stochmal, M. Lurzyńska, M. Bałajewicz-Nowak
{"title":"多囊卵巢综合征患者的血浆皮质醇水平在晚上高于早上。","authors":"M. Kiałka, Agnieszka Ociepka, T. Milewicz, M. Krzyczkowska-Sendrakowska, Katarzyna Gosztyła, E. Stochmal, M. Lurzyńska, M. Bałajewicz-Nowak","doi":"10.1530/ENDOABS.41.GP27","DOIUrl":null,"url":null,"abstract":"INTRODUCTION\nThe aim of our study was to assess the morning and evening cortisol plasma levels in women with polycystic ovary syndrome (PCOS).\n\n\nMATERIAL AND METHOD\n95 patients gave their informed consent to participate in the study and were divided into 2 groups. Group A consisted of 40 PCOS patients and group B consisted of 55 women without features of PCOS. Between day 5 and 8 of the menstrual cycle, morning (7 am), fasting blood samples were taken for the assessment of luteinizng hormone (LH), follicle stimulating hormone (FSH), estradiol, cortisol, prolactin, thyreotropin (TSH), testosterone and dehydroepeiandrosterone (DHEAS). Evening (5 pm) blood samples were also taken for the evaluation of plasma cortisol level\n\n\nRESULTS\nThere were no differences in mean age, body mass index (BMI), FSH, SHBG, PRL, estradiol and TSH levels between group A and group B. Mean plasma LH level was higher in group A compared to group B (10.7 ± 6.8 IU/l vs 6.6 ± 4.5 LU/l, p < 0.02). Mean plasma testosterone and DHEAS levels were also higher in PCOS patients (3.8 ± 0.6 nmol/l vs 1.63 ± 0.6 nmol/l; 427.7 ± 162.9 vs 236.6 ± 97.8 respectively, p < 0.001). Mean evening plasma cortisol level was higher in PCOS patients (11.8 ± 4.1 ug/dl vs 4.7 ± 1.3 ug/dl, p < 0.02). Mean morning plasma cortisol levels did not differ between groups.\n\n\nCONCLUSION\nPCOS women showed the increased evening plasma cortisol level with impacted diurnal secretion rate.","PeriodicalId":21148,"journal":{"name":"Przeglad lekarski","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2016-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"6","resultStr":"{\"title\":\"Evening not morning plasma cortisol level is higher in women with polycystic ovary syndrome.\",\"authors\":\"M. Kiałka, Agnieszka Ociepka, T. Milewicz, M. Krzyczkowska-Sendrakowska, Katarzyna Gosztyła, E. Stochmal, M. Lurzyńska, M. Bałajewicz-Nowak\",\"doi\":\"10.1530/ENDOABS.41.GP27\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"INTRODUCTION\\nThe aim of our study was to assess the morning and evening cortisol plasma levels in women with polycystic ovary syndrome (PCOS).\\n\\n\\nMATERIAL AND METHOD\\n95 patients gave their informed consent to participate in the study and were divided into 2 groups. Group A consisted of 40 PCOS patients and group B consisted of 55 women without features of PCOS. Between day 5 and 8 of the menstrual cycle, morning (7 am), fasting blood samples were taken for the assessment of luteinizng hormone (LH), follicle stimulating hormone (FSH), estradiol, cortisol, prolactin, thyreotropin (TSH), testosterone and dehydroepeiandrosterone (DHEAS). Evening (5 pm) blood samples were also taken for the evaluation of plasma cortisol level\\n\\n\\nRESULTS\\nThere were no differences in mean age, body mass index (BMI), FSH, SHBG, PRL, estradiol and TSH levels between group A and group B. Mean plasma LH level was higher in group A compared to group B (10.7 ± 6.8 IU/l vs 6.6 ± 4.5 LU/l, p < 0.02). Mean plasma testosterone and DHEAS levels were also higher in PCOS patients (3.8 ± 0.6 nmol/l vs 1.63 ± 0.6 nmol/l; 427.7 ± 162.9 vs 236.6 ± 97.8 respectively, p < 0.001). Mean evening plasma cortisol level was higher in PCOS patients (11.8 ± 4.1 ug/dl vs 4.7 ± 1.3 ug/dl, p < 0.02). Mean morning plasma cortisol levels did not differ between groups.\\n\\n\\nCONCLUSION\\nPCOS women showed the increased evening plasma cortisol level with impacted diurnal secretion rate.\",\"PeriodicalId\":21148,\"journal\":{\"name\":\"Przeglad lekarski\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-05-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"6\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Przeglad lekarski\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1530/ENDOABS.41.GP27\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Przeglad lekarski","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1530/ENDOABS.41.GP27","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 6

摘要

本研究的目的是评估多囊卵巢综合征(PCOS)妇女早晚皮质醇血浆水平。材料与方法95例知情同意参加研究的患者分为两组。A组40例PCOS患者,B组55例无PCOS特征的女性。在月经周期的第5天至第8天,早上(早上7点),取空腹血样,评估黄体生成素(LH)、促卵泡激素(FSH)、雌二醇、皮质醇、催乳素、促甲状腺激素(TSH)、睾酮和脱氢表雄酮(DHEAS)。结果A组和B组患者的平均年龄、体重指数(BMI)、FSH、SHBG、PRL、雌二醇和TSH水平均无差异。A组患者的平均血浆LH水平高于B组(10.7±6.8 IU/l vs 6.6±4.5 LU/l, p < 0.02)。PCOS患者的平均血浆睾酮和DHEAS水平也更高(3.8±0.6 nmol/l vs 1.63±0.6 nmol/l;分别为427.7±162.9 vs 236.6±97.8 p < 0.001)。PCOS患者平均夜间血浆皮质醇水平较高(11.8±4.1 ug/dl vs 4.7±1.3 ug/dl, p < 0.02)。各组之间的平均早晨血浆皮质醇水平没有差异。结论pcos妇女夜间血浆皮质醇水平升高,影响其昼夜分泌速率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evening not morning plasma cortisol level is higher in women with polycystic ovary syndrome.
INTRODUCTION The aim of our study was to assess the morning and evening cortisol plasma levels in women with polycystic ovary syndrome (PCOS). MATERIAL AND METHOD 95 patients gave their informed consent to participate in the study and were divided into 2 groups. Group A consisted of 40 PCOS patients and group B consisted of 55 women without features of PCOS. Between day 5 and 8 of the menstrual cycle, morning (7 am), fasting blood samples were taken for the assessment of luteinizng hormone (LH), follicle stimulating hormone (FSH), estradiol, cortisol, prolactin, thyreotropin (TSH), testosterone and dehydroepeiandrosterone (DHEAS). Evening (5 pm) blood samples were also taken for the evaluation of plasma cortisol level RESULTS There were no differences in mean age, body mass index (BMI), FSH, SHBG, PRL, estradiol and TSH levels between group A and group B. Mean plasma LH level was higher in group A compared to group B (10.7 ± 6.8 IU/l vs 6.6 ± 4.5 LU/l, p < 0.02). Mean plasma testosterone and DHEAS levels were also higher in PCOS patients (3.8 ± 0.6 nmol/l vs 1.63 ± 0.6 nmol/l; 427.7 ± 162.9 vs 236.6 ± 97.8 respectively, p < 0.001). Mean evening plasma cortisol level was higher in PCOS patients (11.8 ± 4.1 ug/dl vs 4.7 ± 1.3 ug/dl, p < 0.02). Mean morning plasma cortisol levels did not differ between groups. CONCLUSION PCOS women showed the increased evening plasma cortisol level with impacted diurnal secretion rate.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信