孟加拉300例开腹手术中意外发现肠结核的比率

Rahman, Mollah, S. Ullah, Rahim, Islam, Yusuf, Y. Ali
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引用次数: 1

摘要

背景:肠结核的检测对患者的治疗至关重要。目的:了解临床无疑点剖腹手术中肠结核的发生率。方法:本横断面研究于2002年3月至2004年3月在达卡医学院附属医院外科的不同科室进行,为期两年。根据患者的可得性,严格考虑纳入和排除标准,进行有目的的抽样。选取无肺、肠结核疑似、咳嗽、咯血病史、无抗结核药物史、诊断为非结核、手术疑似肠系膜淋巴结肿大、大网膜肿物、回肠肿物、回肠可疑生长、大网膜增厚、疑似结核穿孔等一项或多项标准的患者作为研究人群。从可疑病变处取活检。组织病理学证实为肉芽肿性病变。已知肺结核病例、疑似肺结核、有咳嗽、咯血病史、曾服用抗结核药物、胸片怀疑有肺结核的患者排除在本研究之外。结果:在满足排除纳入标准后,本研究共招募了300例剖腹手术患者,其中38例阳性,占12.7%。最大发病年龄组为21 ~ 30岁,16例(42%)。在所有组织学阳性病例中,肉芽肿性炎症12例(31.6%);719例(50.0%)同时出现肉芽肿和干酪样坏死;此外,7例(18.4%)朗汉巨细胞出现干酪样坏死。结论:结论在术前未怀疑的开腹手术患者中,肠结核的发病率很高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Rate of Incidental Finding of Intestinal Tuberculosis in Preoperatively Unsuspected Laparotomy: Experience of 300 Cases in Bangladesh
Background: Detection of intestinal tuberculosis is very crucial for the management of the patient. Objective: The purpose of the present study was to find out the incidence of intestinal tuberculosis in clinically unsuspected laparotomies. Methodology: This cross-sectional study was conducted in different units of the Department of Surgery at Dhaka Medical College Hospital, Dhaka from March 2002 to March 2004 for a period of two (2) years. Purposive sampling was done according to availability of the patients and strictly considering the inclusion and exclusion criteria. Patients with no suspicion about pulmonary as well as intestinal tuberculosis, history of cough & haemoptysis, no history of antitubercular drug taken, diagnosed as other than tuberculosis, per operative suspicion raised by any one or more of followings criteria like enlarge lymph nodes in mesentery, omental masses, ileocaecal masses, suspicious growth in ileum, omental thickening, perforation suspected by tuberculosis were selected as study population. Biopsy was taken from suspicious lesions. Histopathology was confirmed the granulomatous lesion. Patients with known case of tuberculosis, suspicion about pulmonary tuberculosis, history of cough & haemoptysis, previously treated with antitubercular drugs and chest X-ray with suspicion of pulmonary tuberculosis were excluded from this study. Results: A total number of 300 patients under laparotomy were recruited for this study after fulfilling exclusion and inclusion criteria of which 38 positive cases were found in the study with a percentage of 12.7%. Maximum affected age group was 21 to 30 years which was 16(42%) cases. In all histologically positive cases granulomatous inflammation were found in 12(31.6%); both granuloma & caseation necrosis was reported in 719(50.0%) cases; furthermore, with this Langhan’s giant cell, caseation necrosis were also found in 7(18.4%) cases. Conclusion: In conclusion the incidence of intestinal tuberculosis is very high among the preoperatively unsuspected laparotomy patients.
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