一种犬猫膳食补充剂的体外磷酸盐结合能力

Q3 Pharmacology, Toxicology and Pharmaceutics

Journal of Pharmacy and Nutrition Sciences Pub Date : 2022-12-26 DOI:10.29169/1927-5951.2022.12.08

N. Bruni, E. Martello, R. Adami, G. Meineri, F. Perondi, Annalisa Costale, Elena Rosso, I. Lippi

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引用次数: 0

摘要

高磷血症已被认为是狗和猫慢性肾脏疾病(CKD)的严重和常见并发症。兽医的方法主要是减少饲粮中的磷，并使用磷酸盐(P)粘合剂。在这项体外研究中，我们比较了pH值为3和7的狗和猫的七种不同成分组合的补充剂，以估计P的结合能力。我们的研究结果证实，与碱性条件相比，酸性条件下补充剂的结合能力最好。在相同条件下，以碳酸钙、乳酸-葡萄糖酸钙和壳聚糖为主要成分的两种产品的P结合能力均高于其他产品。

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In Vitro Phosphate Binding Capacity of a Dietary Supplement for Dogs and Cats

Hyperphosphatemia has been recognized as a serious and frequent complication in dogs and cats with Chronic Kidney Disease (CKD). The veterinary approach is mainly based on reducing phosphorus in the diet and with phosphate (P) binders. In this in vitro study we compared seven supplements with a different combination of ingredients for dogs and cats at pH 3 and 7 to estimate the P binding capacity overtime. Our results confirmed the best binding capacity of supplements at acid compared to basic condition. The P binding capacity of two products containing mainly calcium carbonate, calcium lactate-gluconate and chitosan was higher compared to the other tested at the same conditions.

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Journal of Pharmacy and Nutrition Sciences Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (all)

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