{"title":"运动对尿液生物标志物的影响肌肉炎症的标志?","authors":"Isao Okayasu, Hatsumi Kuroiwa, Kanako Shinkawa, Kaori Hayashi, Seiichi Sato, Noboru Iwata, Goichi Tano, Ryo Sekizaki, Kazuyuki Umeda","doi":"10.32907/ro-136-4708405633","DOIUrl":null,"url":null,"abstract":"During active inflammation, arachidonic acid is converted by the enzyme – cyclooxygenase 2 (COX-2) – into prostaglandins such as prostaglandin E2. However, this molecule is technically difficult to measure because it is metabolised very quickly. Isao Okayasu, Emeritus Professor of Kiryu University and Kitasato University, Japan has collaborated with a team of researchers to develop methods to measure a proposed surrogate marker of inflammation, prostaglandin E–major urinary metabolite (PGE-MUM) – a by-product of metabolism that is stable and easy to measure.","PeriodicalId":74685,"journal":{"name":"Research outreach : the outreach quarterly connecting science with society","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Spiking of urinary biomarker with exercise A marker of muscle inflammation?\",\"authors\":\"Isao Okayasu, Hatsumi Kuroiwa, Kanako Shinkawa, Kaori Hayashi, Seiichi Sato, Noboru Iwata, Goichi Tano, Ryo Sekizaki, Kazuyuki Umeda\",\"doi\":\"10.32907/ro-136-4708405633\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"During active inflammation, arachidonic acid is converted by the enzyme – cyclooxygenase 2 (COX-2) – into prostaglandins such as prostaglandin E2. However, this molecule is technically difficult to measure because it is metabolised very quickly. Isao Okayasu, Emeritus Professor of Kiryu University and Kitasato University, Japan has collaborated with a team of researchers to develop methods to measure a proposed surrogate marker of inflammation, prostaglandin E–major urinary metabolite (PGE-MUM) – a by-product of metabolism that is stable and easy to measure.\",\"PeriodicalId\":74685,\"journal\":{\"name\":\"Research outreach : the outreach quarterly connecting science with society\",\"volume\":\"1 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-06-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Research outreach : the outreach quarterly connecting science with society\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.32907/ro-136-4708405633\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Research outreach : the outreach quarterly connecting science with society","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32907/ro-136-4708405633","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Spiking of urinary biomarker with exercise A marker of muscle inflammation?
During active inflammation, arachidonic acid is converted by the enzyme – cyclooxygenase 2 (COX-2) – into prostaglandins such as prostaglandin E2. However, this molecule is technically difficult to measure because it is metabolised very quickly. Isao Okayasu, Emeritus Professor of Kiryu University and Kitasato University, Japan has collaborated with a team of researchers to develop methods to measure a proposed surrogate marker of inflammation, prostaglandin E–major urinary metabolite (PGE-MUM) – a by-product of metabolism that is stable and easy to measure.
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