乳凝胶作为局部给药系统的不断发展的实施:系统回顾

Shambhvi Singh, I. Singh
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引用次数: 2

摘要

凝胶是近年来流行起来的一种新型疏水药物给药技术。该配方是乳液和凝胶的混合物,是一种创新的给药机制。本综述的目的是深入了解乳凝胶的制备和评价,以确定这些剂型的必要性。由于它使用简单,提高了患者的依从性,将在未来得到广泛应用。乳液易于去除,可涂抹,触变性,无油脂,令人愉快,润肤,保质期长,并且是透明的。凝胶有几个优点,但它们的疏水剂的递送是其中之一。为了解决这个问题,一种基于乳化的技术正在被开发出来。乳凝胶是一种独特的局部给药技术,因为它同时具有凝胶和乳液释放控制系统。当乳剂与凝胶混合作为一种给药形式时,产生具有双重释放的乳剂。具有更好释放模式的聚合物作为这种方法的结果出现了,允许控制和延长释放。关键词:乳液,胶凝剂,聚合物,乳液,草药乳液
本文章由计算机程序翻译,如有差异,请以英文原文为准。
EVOLVING IMPLEMENTATION OF EMULGEL AS A TOPICAL DRUG DELIVERY SYSTEM: A SYSTEMATIC REVIEW
Emulgels are a new drug delivery technology for hydrophobic drugs that have received popularity in recent years. This formulation is a blend of emulsion and gel, and it is an innovative type of drug delivery mechanism. The goal of this review is to gain insight into emulgel preparation and evaluation to determine how essential these dosage forms are. It will be widely utilized in the future since it is simple to use and improves patient compliance. Emulgels are readily removed, spreadable, thixotropic, greaseless, pleasant, emollient, have a long shelf life, and are clear. Gels have several advantages, but their delivery of hydrophobic agents is one of them. To solve this constraint, an emulsion-based technique is being developed. Emulgel is a unique topical medication delivery technology since it has both a gel and an emulsion release control system. When emulsions are mixed with gel as a form of administration, an emulgel with the dual release is created. Polymers with better release patterns have emerged as a consequence of this method, allowing for a controlled and extended-release. KEYWORDS: Emulgel, gelling agent, polymers, emulsions, herbal emulgel
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