{"title":"儿童脊柱侧凸中细胞保存器处理血液的评价","authors":"Elena García, P. Rey, E. Martínez","doi":"10.21203/rs.3.rs-22710/v1","DOIUrl":null,"url":null,"abstract":"Introduction:We study the hematological and microbiological characteristics from the autologous \nblood processed through the intraoperative cell saver used in our centre (Orthopat®) during the \ncorrection of pediatric scoliosis, which is known to be a potentially bleeding surgery. \nMaterial and methods: Descriptive analysis of 31 patients undergoing pediatric scoliosis surgery. All \nof them received blood processed by cell saver intraoperatively. The variables collected were: \ndemographic data, volume of the autogenous red blood cell (RBC) concentrate, blood count, \nbiochemistry, blood culture, preoperative and postoperative blood tests of the patients, incidence \nof fever during reinfusion of RBC concentrate, postoperative surgical site infections and length of \nhospital stay. \nResults: Average volume obtained 288.06ml (sd 154.68). Hematocrit 70.38% (sd 10.03) in \naccordance with cell-saver commercial data (75%). Of the blood samples obtained, 42.86% had \nblood cultures that were positive for aerobes and 48.28% for anaerobes. The relation between \npostoperative infections and contamination of blood concentrates was not statistically significant. \nWhen comparing the pre-surgery and post-surgery analytical samples, statistically significant \ndifferences (p <0.05) were found in the following: hemoglobin and hematocrit decreased in the \npostoperative period, while coagulation parameters show a tendency to coagulopathy. \nConclusion: Our cell saver obtains RBC concentrates with a percentage of hematocrit in agreement \nwith available information. The reinfusion of them is safe from an infectious and biochemical point \nof view, but its immunological implications are not clear. This surgery continues to result in a \nsignificant loss of blood. Measures taken to avoid allogenic transfusions remain necessary and \nshould be enhanced.","PeriodicalId":14122,"journal":{"name":"International Journal of Medical Research and Health Sciences","volume":"7 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"EVALUATION OF BLOOD PROCESSED BY CELL SAVER IN PEDIATRIC SCOLIOSIS\",\"authors\":\"Elena García, P. Rey, E. Martínez\",\"doi\":\"10.21203/rs.3.rs-22710/v1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Introduction:We study the hematological and microbiological characteristics from the autologous \\nblood processed through the intraoperative cell saver used in our centre (Orthopat®) during the \\ncorrection of pediatric scoliosis, which is known to be a potentially bleeding surgery. \\nMaterial and methods: Descriptive analysis of 31 patients undergoing pediatric scoliosis surgery. All \\nof them received blood processed by cell saver intraoperatively. The variables collected were: \\ndemographic data, volume of the autogenous red blood cell (RBC) concentrate, blood count, \\nbiochemistry, blood culture, preoperative and postoperative blood tests of the patients, incidence \\nof fever during reinfusion of RBC concentrate, postoperative surgical site infections and length of \\nhospital stay. \\nResults: Average volume obtained 288.06ml (sd 154.68). Hematocrit 70.38% (sd 10.03) in \\naccordance with cell-saver commercial data (75%). Of the blood samples obtained, 42.86% had \\nblood cultures that were positive for aerobes and 48.28% for anaerobes. The relation between \\npostoperative infections and contamination of blood concentrates was not statistically significant. \\nWhen comparing the pre-surgery and post-surgery analytical samples, statistically significant \\ndifferences (p <0.05) were found in the following: hemoglobin and hematocrit decreased in the \\npostoperative period, while coagulation parameters show a tendency to coagulopathy. \\nConclusion: Our cell saver obtains RBC concentrates with a percentage of hematocrit in agreement \\nwith available information. The reinfusion of them is safe from an infectious and biochemical point \\nof view, but its immunological implications are not clear. This surgery continues to result in a \\nsignificant loss of blood. Measures taken to avoid allogenic transfusions remain necessary and \\nshould be enhanced.\",\"PeriodicalId\":14122,\"journal\":{\"name\":\"International Journal of Medical Research and Health Sciences\",\"volume\":\"7 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-04-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Medical Research and Health Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.21203/rs.3.rs-22710/v1\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Medical Research and Health Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21203/rs.3.rs-22710/v1","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
EVALUATION OF BLOOD PROCESSED BY CELL SAVER IN PEDIATRIC SCOLIOSIS
Introduction:We study the hematological and microbiological characteristics from the autologous
blood processed through the intraoperative cell saver used in our centre (Orthopat®) during the
correction of pediatric scoliosis, which is known to be a potentially bleeding surgery.
Material and methods: Descriptive analysis of 31 patients undergoing pediatric scoliosis surgery. All
of them received blood processed by cell saver intraoperatively. The variables collected were:
demographic data, volume of the autogenous red blood cell (RBC) concentrate, blood count,
biochemistry, blood culture, preoperative and postoperative blood tests of the patients, incidence
of fever during reinfusion of RBC concentrate, postoperative surgical site infections and length of
hospital stay.
Results: Average volume obtained 288.06ml (sd 154.68). Hematocrit 70.38% (sd 10.03) in
accordance with cell-saver commercial data (75%). Of the blood samples obtained, 42.86% had
blood cultures that were positive for aerobes and 48.28% for anaerobes. The relation between
postoperative infections and contamination of blood concentrates was not statistically significant.
When comparing the pre-surgery and post-surgery analytical samples, statistically significant
differences (p <0.05) were found in the following: hemoglobin and hematocrit decreased in the
postoperative period, while coagulation parameters show a tendency to coagulopathy.
Conclusion: Our cell saver obtains RBC concentrates with a percentage of hematocrit in agreement
with available information. The reinfusion of them is safe from an infectious and biochemical point
of view, but its immunological implications are not clear. This surgery continues to result in a
significant loss of blood. Measures taken to avoid allogenic transfusions remain necessary and
should be enhanced.