探讨窄带UVB治疗白癜风证据应用的空白

L. Madigan, M. Al-Jamal, I. Hamzavi
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引用次数: 13

摘要

虽然窄带紫外线B (NB - UVB)已成为弥漫性白癜风治疗不可或缺的一部分,但在剂量和给药方面缺乏基于证据的指南。这在很大程度上是由于异质的研究设计、不明确的方法、不同的给药策略以及使用不同的、有些武断的结果测量。在缺乏前瞻性试验来解决这些问题的情况下,我们回顾了有关NB - UVB在白癜风中的应用的现有文献,作者现在向光疗界提出了一系列问题,试图突出我们理解中的差距。我们的目标是激发讨论,征求专家意见,并确定未来研究的领域,以便为受这种疾病折磨的患者制定统一和安全的治疗指南。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Exploring the gaps in the evidence‐based application of narrowband UVB for the treatment of vitiligo
While narrowband ultraviolet light B (NB‐UVB) has become integral to the treatment of diffuse vitiligo, evidence‐based guidelines have been lacking with regard to dosing and administration. This is largely the result of heterogeneous study designs, ambiguous methodologies, disparate dosing strategies, and the use of varied, and somewhat arbitrary, outcome measures. In the absence of prospective trials to address each of these concerns, the available literature regarding the application of NB‐UVB for vitiligo was reviewed and the authors now pose a set of questions to the phototherapy community in an attempt to highlight gaps within our understanding. We aim to stimulate discussion, elicit expert opinion, and identify areas for future research to move toward a unified and safe treatment guideline for patients afflicted by this disease.
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