T. Mori, A. Yogo, Y. Arikawa, T. Hayakawa, S. R. Mirfayzi, Z. Lan, T. Wei, Y. Abe, M. Nakai, K. Mima, H. Nishimura, S. Fujioka, R. Kodama
{"title":"激光驱动中子源在医药领域应用的可行性研究","authors":"T. Mori, A. Yogo, Y. Arikawa, T. Hayakawa, S. R. Mirfayzi, Z. Lan, T. Wei, Y. Abe, M. Nakai, K. Mima, H. Nishimura, S. Fujioka, R. Kodama","doi":"10.1017/hpl.2023.4","DOIUrl":null,"url":null,"abstract":"Abstract We predict the production yield of a medical radioisotope \n${}^{67}$\n Cu using \n${}^{67}$\n Zn(n, p) \n${}^{67}$\n Cu and \n${}^{68}$\n Zn(n, pn) \n${}^{67}$\n Cu reactions with fast neutrons provided from laser-driven neutron sources. The neutrons were generated by the p+ \n${}^9\\mathrm{Be}$\n and d+ \n${}^9$\n Be reactions with high-energy ions accelerated by laser–plasma interaction. We evaluated the yield to be (3.3 \n$\\pm$\n 0.5) \n$\\times$\n 10 \n${}^5$\n atoms for \n${}^{67}$\n Cu, corresponding to a radioactivity of 1.0 \n$\\pm$\n 0.2 Bq, for a Zn foil sample with a single laser shot. Using a simulation with this result, we estimated \n${}^{67}$\n Cu production with a high-frequency laser. The result suggests that it is possible to generate \n${}^{67}$\n Cu with a radioactivity of 270 MBq using a future laser system with a frequency of 10 Hz and 10,000-s radiation in a hospital.","PeriodicalId":54285,"journal":{"name":"High Power Laser Science and Engineering","volume":"11 1","pages":""},"PeriodicalIF":5.2000,"publicationDate":"2023-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Feasibility study of laser-driven neutron sources for pharmaceutical applications\",\"authors\":\"T. Mori, A. Yogo, Y. Arikawa, T. Hayakawa, S. R. Mirfayzi, Z. Lan, T. Wei, Y. Abe, M. Nakai, K. Mima, H. Nishimura, S. Fujioka, R. Kodama\",\"doi\":\"10.1017/hpl.2023.4\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Abstract We predict the production yield of a medical radioisotope \\n${}^{67}$\\n Cu using \\n${}^{67}$\\n Zn(n, p) \\n${}^{67}$\\n Cu and \\n${}^{68}$\\n Zn(n, pn) \\n${}^{67}$\\n Cu reactions with fast neutrons provided from laser-driven neutron sources. The neutrons were generated by the p+ \\n${}^9\\\\mathrm{Be}$\\n and d+ \\n${}^9$\\n Be reactions with high-energy ions accelerated by laser–plasma interaction. We evaluated the yield to be (3.3 \\n$\\\\pm$\\n 0.5) \\n$\\\\times$\\n 10 \\n${}^5$\\n atoms for \\n${}^{67}$\\n Cu, corresponding to a radioactivity of 1.0 \\n$\\\\pm$\\n 0.2 Bq, for a Zn foil sample with a single laser shot. Using a simulation with this result, we estimated \\n${}^{67}$\\n Cu production with a high-frequency laser. The result suggests that it is possible to generate \\n${}^{67}$\\n Cu with a radioactivity of 270 MBq using a future laser system with a frequency of 10 Hz and 10,000-s radiation in a hospital.\",\"PeriodicalId\":54285,\"journal\":{\"name\":\"High Power Laser Science and Engineering\",\"volume\":\"11 1\",\"pages\":\"\"},\"PeriodicalIF\":5.2000,\"publicationDate\":\"2023-01-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"High Power Laser Science and Engineering\",\"FirstCategoryId\":\"101\",\"ListUrlMain\":\"https://doi.org/10.1017/hpl.2023.4\",\"RegionNum\":1,\"RegionCategory\":\"物理与天体物理\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"OPTICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"High Power Laser Science and Engineering","FirstCategoryId":"101","ListUrlMain":"https://doi.org/10.1017/hpl.2023.4","RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OPTICS","Score":null,"Total":0}
Feasibility study of laser-driven neutron sources for pharmaceutical applications
Abstract We predict the production yield of a medical radioisotope
${}^{67}$
Cu using
${}^{67}$
Zn(n, p)
${}^{67}$
Cu and
${}^{68}$
Zn(n, pn)
${}^{67}$
Cu reactions with fast neutrons provided from laser-driven neutron sources. The neutrons were generated by the p+
${}^9\mathrm{Be}$
and d+
${}^9$
Be reactions with high-energy ions accelerated by laser–plasma interaction. We evaluated the yield to be (3.3
$\pm$
0.5)
$\times$
10
${}^5$
atoms for
${}^{67}$
Cu, corresponding to a radioactivity of 1.0
$\pm$
0.2 Bq, for a Zn foil sample with a single laser shot. Using a simulation with this result, we estimated
${}^{67}$
Cu production with a high-frequency laser. The result suggests that it is possible to generate
${}^{67}$
Cu with a radioactivity of 270 MBq using a future laser system with a frequency of 10 Hz and 10,000-s radiation in a hospital.
期刊介绍:
High Power Laser Science and Engineering (HPLaser) is an international, peer-reviewed open access journal which focuses on all aspects of high power laser science and engineering.
HPLaser publishes research that seeks to uncover the underlying science and engineering in the fields of high energy density physics, high power lasers, advanced laser technology and applications and laser components. Topics covered include laser-plasma interaction, ultra-intense ultra-short pulse laser interaction with matter, attosecond physics, laser design, modelling and optimization, laser amplifiers, nonlinear optics, laser engineering, optical materials, optical devices, fiber lasers, diode-pumped solid state lasers and excimer lasers.