移植干细胞对实验性肌肉损伤兔血清钾水平的影响

N. Stadnyk, A. Mazurkevich
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摘要

在兽医学中,运动和工作动物的肢体肌肉损伤,如撕裂、扭伤和骨骼肌损伤是常见的。这些损伤给动物带来了挑战性的问题,因为传统的治疗时间很长,而且并不总是成功。在动物中,骨骼肌是具有可塑性和动态性的组织,能够适应不同的条件,如纤维类型的变化和肥大,并能从损伤中恢复。本文的主要目的是讨论、分析和总结旨在利用同种异体间充质干细胞作为再生治疗手段在兽医实践中的研究结果。细胞治疗的主要方向是利用同种异体间充质干细胞(MSCs)。这些细胞是未分化的,可以自我更新,这使它们能够发育成具有特定功能的细胞,并成为组织修复的有效治疗方法。特别是间充质干细胞,由于其易于分离和培养,并且在其使用方面没有伦理问题,因此在兽医学方面具有很大的前景。本文结合科学研究和作者的研究成果,讨论了异体间充质干细胞用于组织修复的分析在兽医学实验动物中的应用。使用一种基于细胞再生的创新和有前途的治疗动物受损肌肉组织的方法,可以显着加速动物受伤后的恢复,并避免传统治疗方法所产生的副作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
THE LEVEL OF POTASSIUM IN THE BLOOD SERUM OF RABBITS WITH EXPERIMENTAL MUSCLE DAMAGE UNDER THE INFLUENCE OF TRANSPLANTED STEM CELLS
In veterinary medicine, limb muscle injuries in sports and working animals, such as tears, sprains, and skeletal muscle damage, are common. These injuries pose challenging problems in animals because traditional treatments are lengthy and not always successful. In animals, skeletal muscles are plastic and dynamic tissues that can adapt to different conditions, such as fiber type changes and hypertrophy, and recover from injuries. The main purpose of this article is to discuss, analyze and summarize the results of research aimed at the use of allogeneic mesenchymal stem cells, a means of regenerative therapy, in veterinary practice. The main direction of cell therapy is the use of allogeneic mesenchymal stem cells (MSCs). These cells are undifferentiated and can renew themselves, which allows them to develop into cells with specific functions and become an effective treatment for tissue repair. In particular, mesenchymal stem cells are promising for veterinary medicine, as they are easy to isolate and cultivate and have no ethical issues regarding their use. The article discusses the application of the analysis of the use of allogeneic mesenchymal stem cells for tissue repair in veterinary medicine in experimental animals, taking into account scientific research and the results of the authors' research. The use of an innovative and promising method of treating animals with damaged muscle tissue based on cellular regeneration can significantly accelerate the recovery of animals after injury and avoid the side effects that occur with traditional methods of treatment.
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