S. Sushanth Kumar, K. Rangaiah, A. Cherukumudi, P. Dash, B. Barooah
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引用次数: 0
摘要
目的:二尖瓣狭窄(MS)在儿童和青少年中很少见,但在风湿热仍然流行的发展中国家并不罕见。在印度,风湿性MS通常影响儿童和20岁以下的年轻人(青少年二尖瓣狭窄)。虽然经皮经静脉二尖瓣合气道切开术(PTMC)中使用ACCURA球囊导管已被证明是一种安全有效的技术,在大量成人患者中,该技术在儿童中的报道很少。在我们的研究中,我们旨在评估50例年龄≤20岁的风湿性MS患者PTMC的即时和早期随访结果,并与> 20岁的患者进行比较。方法:连续50例年龄≤20岁且符合入选标准且瓣膜适合PTMC的有症状的风湿性MS患者为病例,另连续50例年龄> 20岁且具有相似特征的患者为对照组。两组均按标准方案进行PTMC,并记录血流动力学和超声心动图参数。使用适当的统计检验来比较这些数据。结果:在二尖瓣面积(MVA) 0.77(0.16) cm 2比0.86(0.15)cm 2 (p<0.0069)时,青少年组多发性硬化症的发生率高于成年组
Comparative study of percutaneous transvenous mitral commissurotomy using ACCURA balloon in juvenile vs adult rheumatic mitral stenosis
Objective: Mitral stenosis (MS) is rarely seen in children and adolescents but is not uncommon in developing countries where rheumatic fever is still endemic. Rheumatic MS in India commonly affects children and young adults less than 20 years old (juvenile mitral stenosis). Although percutaneous transvenous mitral commissurotomy (PTMC) using the ACCURA balloon catheter has been shown to be safe and effective technique in large series of adult patients, reports of this technique in children are scarce. In our study, we aim to evaluate the immediate and early follow-up results of PTMC in 50 patients of rheumatic MS age ≤ 20 years and compare the same with those of the patients aged > 20 years . Methods: Fifty consecutive patients aged ≤ 20 years with symptomatic rheumatic MS who met the inclusion criteria and whose valves are suitable for PTMC formed the cases, another 50 consecutive patients aged > 20 years with similar characteristics formed the control group. PTMC was done for both the groups as per the standard protocol and hemodynamic and echocardiography parameters were noted. Appropriate statistical tests were used to compare these data. Results: The juvenile group had more often severe MS than adult patients at baseline [mitral valve area (MVA) 0.77(0.16) cm 2 vs. 0.86(0.15) cm 2 , p<0.0069