367例糖尿病患者的卢瑟福5期是干细胞治疗外周动脉疾病的最佳适应症

Bertrand Lehalle , Philippe Jan , Jean-François Stoltz
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引用次数: 2

摘要

干细胞疗法目前似乎正在突破科学的极限。然而,从临床医生的角度来看,许多结果必须相对化,因为效率和相关性标准离实际现实很远。因此,我们对干细胞治疗在外周动脉疾病患者的潜在应用产生了兴趣。通过一项回顾性临床研究,我们确定了一组患者,在公共卫生和成本方面,细胞治疗可能有潜在的兴趣。我们证明了这一组对应于卢瑟福5期的糖尿病患者。对于这组患者,我们为干细胞治疗临床试验铺平了道路,与传统护理相关,以伤口愈合时间和再干预率为终点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Diabetic patients on Rutherford's stage 5 is the best indication of stem cell therapy in peripheral artery disease: A retrospective study on 367 patients

Stem cell therapy currently seems to be pushing back limits to science. However, on the clinician's perspective, many results must be relativized, since efficiency and relevancy criterion are far away from practical reality. Therefore, we took an interest in the potential use of stem cell therapy in patients with peripheral artery disease. Through a retrospective clinical study, we identified a group of patients in which cell therapy could potentially be of interest, in terms of public health and cost. We demonstrated that this group corresponds to diabetic patients on Rutherford's stage 5. For this group of patients, we pave the way for a stem cell therapy clinical trial, associated with conventional care, with wound healing time and reintervention rate as endpoints.

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