他汀类药物治疗脑卒中后癫痫的最新进展

Q4 Medicine

中华神经医学杂志 Pub Date : 2020-02-15 DOI:10.3760/CMA.J.ISSN.1671-8925.2020.02.020

Y. Li, Zhengli Di, Xurong Zhu

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引用次数: 0

摘要

脑卒中后癫痫(PSE)作为脑卒中后常见的并发症之一，往往严重影响患者的生活质量。近年来，越来越多的研究发现他汀类药物可以保护血脑屏障的完整性，减轻神经递质兴奋性毒性损伤，减少神经元凋亡，减少神经炎症，起到脑保护作用，从而降低PSE的风险。本文就PSE的治疗及他汀类药物在PSE中的应用作一综述。关键词:卒中;癫痫;他汀类药物

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Recent advance in statins in post-stroke epilepsy

Post-stroke epilepsy (PSE), as one of the common complications after stroke, often seriously affect the quality of life of the survivors. In recent years, more and more studies have found that statins can protect the integrity of blood-brain barrier, alleviate excitotoxic damage of neurotransmitters, reduce neuronal apoptosis, and reduce neuroinflammation, which play a role in brain protection, thereby reducing the risk of PSE. This article reviews the treatment of PSE and application of statins in PSE. Key words: Stroke; Epilepsy; Statins

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来源期刊

中华神经医学杂志 Psychology-Neuropsychology and Physiological Psychology

CiteScore

0.30

自引率

0.00%

发文量

6272

期刊介绍：