病态肥胖患者药物剂量计算的研究

Farmacia Hospitalaria (English Edition) Pub Date : 2009-01-01 DOI:10.1016/S2173-5085(09)70097-8

G. Serra Soler , N. Galán Ramos , I. Martínez-López , O. Delgado Sánchez , J. Quevedo Juanals

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引用次数: 6

摘要

本研究的目的是分析住院病态肥胖患者药物剂量计算的适宜性和特点。方法回顾性、描述性研究某三级医院2007年住院病态肥胖患者用药剂量计算情况。由药剂科准备的建议被用作标准。结果纳入62例患者。每位患者的平均药物处方数为12.1(4-39)，建议中列出的平均药物处方数为2.4(1-10)。共开了135种药物。上述81例(60%)的剂量计算与建议一致，54例(40%)不一致;用药不足51例，用药过量3例。讨论全体性抗生素和抗凝血酶药物组均存在用药不当，用药不足比用药过量更为常见。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Study of drug dose calculation for morbidly obese patients

Introduction

The objective of this study is to analyse the appropriateness and characteristics of drug dose calculation for hospitalised, morbidly obese patients.

Methods

Retrospective, descriptive study of dose calculations for drugs prescribed to hospitalised, morbidly obese patients in a tertiary hospital in 2007. The recommendations prepared by the Pharmacy division are used as a standard.

Results

We included 62 patients. The mean number of medications prescribed per patient was 12.1 (4–39), and an average of 2.4 (1–10) are listed in the recommendations. A total of 135 drugs were prescribed. Dose calculations for 81 of the above (60%) coincided with recommendations and 54 (40%) did not; there were 51 cases of underdosing and three cases of overdosing.

Discussion

Improper dosing was detected for prescriptions in the systemic antibiotic and antithrombin drug groups, with underdosing being more common than overdosing.

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Farmacia Hospitalaria (English Edition)

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