肥大细胞在色素沉着障碍中的作用

Pigment International Pub Date : 2021-05-01 DOI:10.4103/pigmentinternational.pigmentinternational_24_21

V. Nielsen, S. Thomsen

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引用次数: 0

摘要

肥大细胞通过分泌组胺是炎症反应的关键介质。虽然组胺目前不被认为是一种黑素，但最近的研究表明，组胺的释放可诱导黑素形成、黑素细胞增殖和迁移。在这里，我们讨论肥大细胞和黑素细胞之间的复杂关系，以及它在色素沉着障碍的影响目前的证据。

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The role of the mast cell in pigmentation disorders

The mast cell is a critical mediator of the inflammatory response by secreting histamine. While histamine is currently not regarded as a melanogen, recent studies have shown histamine release to induce melanogenesis, melanocyte proliferation and migration. Herein, we discuss the current evidence of the complex relationship between the mast cell and melanocyte, and its impact in pigmentation disorders.

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Pigment International

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0.00%

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审稿时长

27 weeks