增加ω - 3 PUFA含量的海豹油对无菌仔猪免疫参数的影响

V. Révajová, J. Pistl, R. Kaštel, L. Bindas, D. Magic, M. Levkut, A. Bomba, J. Šajbidor
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引用次数: 9

摘要

与对照组相比,无菌仔猪口服ω - 3多不饱和脂肪酸含量增加的油,导致外周血CD4、CD8淋巴细胞、B淋巴细胞和单核细胞的总价值显著增加。吞噬细胞的代谢活性和淋巴细胞的多克隆活性未受显著影响。根据血清中生长激素测定,生长因子水平明显升高。生化指标显示血清二十碳五烯酸和二十二碳六烯酸水平显著升高,花生四烯酸水平显著降低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Influencing the immune parameters in germ‐free piglets by administration of seal oil with increased content of ω‐3 PUFA
Oral administration of oil with an increased content of ω‐3 polyunsarurated fatty acids to germfree piglets resulted in a significant increase in the total values of CD4, CD8 lymphocytes, B lymphocytes, and monocytes, in peripheral blood in comparison with the controls. The metabolic activities of phagocytes as well as the polyclonal activation of lymphocytes were not significantly influenced. The level of growth factor was significantly higher, as determined on the basis of somatomedin in the blood serum. Biochemical indices showed a significant increase in the level of eicosapentaenoic and docosahexaenoic acids in blood serum and the decrease in the level of arachidonic acid at the same time.
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