基于高分子胶束的药物输送系统

P. Khot, K. Nangare, Vaishali S. Payghan, Tejashree Kamble, Payghan Santosh
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引用次数: 1

摘要

高分子胶束作为疏水药物的纳米载体已被广泛研究。它们可以被设计成具有持续时间和血液循环的强度,以及与癌细胞表面某些高度应激受体的结合特异性。将这些药物掺入纳米颗粒可减少标准化疗对健康组织的不良影响。这些被认为是药物运输载体的纳米颗粒是多功能的,包括胶束、脂质体、树状大分子、纳米胶囊、纳米球等等。高分子胶束作为疏水药物的纳米载体已被广泛研究。它们可以被设计成具有持续时间和循环的强度,以及与癌细胞表面表达的某些更多受体的结合规格。当这些药物诱导的纳米颗粒到达植物表面时,可以使用外部刺激,如超声波,来引入局部和暂时的药物释放。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Drug Delivery Systems Based on Polymeric Micelles
Polymeric micelles have been extensively studied as nanocarriers for hydrophobic drugs. They can be designed to have the intensity of duration and blood circulation, as well as binding specificity to certain highly stressed receptors on the surface of cancer cells. y. The incorporation of these agents into nanoparticles reduces the adverse effects of standard chemotherapy on healthy tissues. Such nanoparticles, considered to be drug-transporting vehicles, are versatile and include micelles, liposomes, dendrimers, nanocapsules, nanospheres and more. Polymeric micelles have been extensively studied as nanocarriers for hydrophobic drugs. They can be designed to have the intensity of duration and circulation, as well as binding specifications to certain more receptors expressed on the surface of cancer cells. When these drug-induced nanoparticles reach the plant surface, an external stimulus, such as ultrasound, can be used to introduce local and temporary drug release.
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