草药:传递草药药物的新方法综述

A. Londhe, S. Mankar
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引用次数: 1

摘要

草药和草药化合物由于其众多的治疗应用而引起了极大的研究兴趣。一些民间证据已被记录在古代世界药物系统的配方中,这些证据吸引了研究人员进行科学验证。一些草药物质已经被发现并证明了对病理生理疾病的治疗效果。最近,有人尝试用这些草药成分合成用于生物医学用途的纳米颗粒。绿色合成是使用草药/生物原料制造纳米颗粒的方法,它已经生产了许多金属纳米颗粒。金属纳米颗粒-中药组合可能对不同的病理生理条件表现出更好的疗效。本文综述了不同草药资源形成的不同金属纳米颗粒及其在健康和疾病中的作用。纳米颗粒的绿色合成是一个新兴的研究领域,但关于其生理效应、相容性和毒性的数据很少。本文就重要药用植物在金属纳米颗粒合成中的作用、生理相容性和治疗效果等方面作一综述。此外,还考虑和讨论了纳米颗粒绿色合成的局限性(毒性)及其在健康和疾病方面的未来前景。这一综述为将纳米技术与草药相结合的药用植物研究打开了一个全新的维度,即草药。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Herbonanoceuticals: A Newer approach for Delivering Herbal Drugs-A Review
Herbs and herbal compounds are of tremendous research interest due to their numerous therapeutic applications. Several folk evidences have been documented in the formulations of the ancient world's pharmaceutical system, which have drawn researchers for scientific validation. Several herbal substances have been found and demonstrated therapeutic efficacy against pathophysiological diseases. Recently, attempts have been made to use these herbal components to synthesize nanoparticles for biomedical uses. Green synthesis is the method of creating nanoparticles using herbal/biogenic materials, and it has produced numerous metallic nanoparticles. The metal nanoparticle-herb combination may show better efficacy against different pathophysiological conditions. This review tries to put forward the different metal nanoparticles formed from different herbal resources and their role in health and diseases. Although green synthesis of nanoparticle is an emerging area of research but very few data are available regarding their physiological effects, compatibility and toxicity. This review is an effort to elaborate in detail the role of medicinally important herbs in synthesizing metal nanoparticles, their physiological compatibility and therapeutic efficacy. Further, considerations and discussions are also made on limitations (toxicity) of the green synthesis of nanoparticles along with their future prospects in health and diseases. This review opens door to a completely new dimension in medicinal plant research combining the nanotechnology with herbs i.e., Herbonanoceuticals.
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