坦桑尼亚Biharamulo地区对治疗尿路感染药用植物认知的民族植物学调查

Frenk B. Paschal, E. Mwega, G. Bakari
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摘要

为了克服抗生素耐药性(AMR)的灾难性灾难,许多研究人员对安全有效的抗菌药用植物感兴趣。目的:通过对坦桑尼亚Kagera地区Biharamulo地区的民族植物学调查,鉴定治疗尿路感染(UTI)的药用植物。材料与方法:采用半结构式问卷调查方法,对尿路感染及其中药的社会认知进行评估。对UTI药材进行鉴定和采集。民族植物学资料采用SPSS 16版卡方检验进行分析。在p值< 0.05的统计显著性差异下,被试的认知被证明是合理的。结果:研究发现大多数参与者了解UTI及其药用植物,因为他们知道临床症状(85.2%),传播方式和病因(41%),UTI草药(99.5%),其中大多数人使用草药治疗UTI的比例为92.8%。在42种声称和确定用于治疗UTI的药用植物中,文献综述中29种(69%)具有治疗UTI或相关抗菌感染的药理学支持,这些感染归因于构成植物化学物质。42种药用植物分属20科,以紫金桃科、豆科和兰科为主,各占15%。在治疗上,几内亚葡萄球菌、cordatum葡萄球菌、C. citrinus葡萄球菌、T. mollis葡萄球菌、cercea葡萄球菌、X. caffra葡萄球菌、A. muricata葡萄球菌、P. granatum葡萄球菌、J. mimosifolia葡萄球菌和N. macrophylla葡萄球菌对UTI微生物具有较强的抗菌活性。结论:本研究结果与以往的研究结果一致,即社会对尿路感染及其药用植物有一定的认识。本研究结果为传统医师和中草药医师所宣称的利用所选药用植物治疗尿路感染的微生物疗效提供了有力的依据和支持,因此本研究可能为进一步发现新的尿路感染药物提供方向和范围。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Ethnobotanical Survey on Awareness of Medicinal Plants Used for Treatment of Urinary Tract Infection in Biharamulo District: TanzaniaC
Introduction: In overcoming a catastrophic disaster of antimicrobial resistance (AMR), many researchers are interested with safe and active antimicrobial medicinal plants. Objective: This study aimed to identify medicinal plants used for treatment of Urinary tract infection (UTI) through ethnobotanical survey, conducted in Biharamulo district at Kagera region in Tanzania. Materials and Methods: To assess the societal awareness on UTI and its curative herbs, semi-structured questionnaires were employed. UTI herbs were identified and collected. The ethnobotanical data were analysed by using Chi-square test in SPSS version 16. Awareness of participants were justified at the statistical significance difference of p-values < 0.05. Results: The study found most participants to have awareness on UTI and its medicinal plants, because they identified clinical signs (85.2%), mode of transmission and aetiology (41%), UTI herbs (99.5%) and most of them used herbs to treat UTI for 92.8%. Out of the 42 medicinal plants claimed and identified for treating UTI, 29 (69%) of them had pharmacological supported for treating UTI or related antimicrobial infections that were attributed to constituted phytochemicals in literature reviews. The 42 medicinal plants belonged in 20 families where by the dominant were Myrtaceae, Leguminosae and Lamiaceae, each one composed 15%. Therapeutically, S. guineense, S. cordatum, C. citrinus, T. mollis, T. cercea, X. caffra, A. muricata, P. granatum, J. mimosifolia and N. macrophylla was documented by the present study for elicit strong antimicrobial activities against UTI microbes. Conclusion: Findings from this study concurred with the previous ones that the society had awareness on UTI and its medicinal plants. The study results were significantly justified and supported the uses of selected medicinal plants for treating UTI with microbial efficacies as claimed by traditional healers and herbalists, hence this study might provide a direction and scope for further discovery of new UTI drugs.
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