介绍了一种改进的变色酸法简便测定甲醇的试剂盒

M. Ghadirzadeh, A. Rafizadeh, A. Fattahi, S. Mirtorabi, Hajar Nazari, M. Rafizadeh
{"title":"介绍了一种改进的变色酸法简便测定甲醇的试剂盒","authors":"M. Ghadirzadeh, A. Rafizadeh, A. Fattahi, S. Mirtorabi, Hajar Nazari, M. Rafizadeh","doi":"10.3844/AJPTSP.2019.1.6","DOIUrl":null,"url":null,"abstract":"Methyl alcohol poisoning usually happens by use of contaminated ethanol. So, development of an easy and cost-effective method to determine methanol in these products can be helpful to diagnosemethanolintoxication. The aim of this paper is introducing a new kit based on chromotropic acid method for measuring the methanol content of alcoholic beverages. In this study, a new modified chromotropic acid method (as a kit) was used to determine of methanol in 700 self-made samples with diverse ethanol concentration prepared by \"add found\" technique. Briefly, in the proposed method, produced formaldehyde by methanol oxidation is reacted with chromotropic acid in a high acidic media. The quantification limit of this kit lies below the permitted dose and safe amount of methanol in the beverages regulated by the European Parliament and the Council. The attained results indicate Limit of Quantification of the method is1250 mg/Land all examined samples with more methanol amounts are easily determined with good accuracy and precision. As for the European standard about permitted dose of methanol in beverages (up to 4000 mg/lin 40% v/v of alcohol strength) and gained results, it seems, this proposed method practically enables rapid and easy quantitative determination of methanol in all kind of alcoholic strength with suitable accuracy and precision. However, conclusive conclusions in this area will require further examination in actual samples of alcoholic beverages. But, to the best of our knowledge, there isn’t any report about such easy method.","PeriodicalId":7769,"journal":{"name":"American Journal of Pharmacology and Toxicology","volume":"76 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":"{\"title\":\"Introducing a New Kit based on Modified Chromotropic Acid Method for Easy Determination of Methanol\",\"authors\":\"M. Ghadirzadeh, A. Rafizadeh, A. Fattahi, S. Mirtorabi, Hajar Nazari, M. Rafizadeh\",\"doi\":\"10.3844/AJPTSP.2019.1.6\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Methyl alcohol poisoning usually happens by use of contaminated ethanol. So, development of an easy and cost-effective method to determine methanol in these products can be helpful to diagnosemethanolintoxication. The aim of this paper is introducing a new kit based on chromotropic acid method for measuring the methanol content of alcoholic beverages. In this study, a new modified chromotropic acid method (as a kit) was used to determine of methanol in 700 self-made samples with diverse ethanol concentration prepared by \\\"add found\\\" technique. Briefly, in the proposed method, produced formaldehyde by methanol oxidation is reacted with chromotropic acid in a high acidic media. The quantification limit of this kit lies below the permitted dose and safe amount of methanol in the beverages regulated by the European Parliament and the Council. The attained results indicate Limit of Quantification of the method is1250 mg/Land all examined samples with more methanol amounts are easily determined with good accuracy and precision. As for the European standard about permitted dose of methanol in beverages (up to 4000 mg/lin 40% v/v of alcohol strength) and gained results, it seems, this proposed method practically enables rapid and easy quantitative determination of methanol in all kind of alcoholic strength with suitable accuracy and precision. However, conclusive conclusions in this area will require further examination in actual samples of alcoholic beverages. But, to the best of our knowledge, there isn’t any report about such easy method.\",\"PeriodicalId\":7769,\"journal\":{\"name\":\"American Journal of Pharmacology and Toxicology\",\"volume\":\"76 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"American Journal of Pharmacology and Toxicology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3844/AJPTSP.2019.1.6\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"American Journal of Pharmacology and Toxicology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3844/AJPTSP.2019.1.6","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 4

摘要

甲醇中毒通常是由于使用受污染的乙醇而发生的。因此,开发一种简单、经济的方法来测定这些产品中的甲醇,有助于诊断半乙醇中毒。介绍了一种基于显色酸法的新型酒精饮料甲醇含量测定试剂盒。本文采用一种改进的变色酸法(试剂盒),对700个不同乙醇浓度的自制样品进行了甲醇含量的测定。简单地说,在提出的方法中,甲醇氧化产生的甲醛在高酸性介质中与变色酸反应。本试剂盒的定量限值低于欧洲议会和理事会规定的饮料中甲醇的允许剂量和安全量。结果表明,该方法的定量限为1250 mg/Land,甲醇含量较高的样品均易于测定,准确度和精密度较高。根据欧洲关于饮料中甲醇允许剂量的标准(不超过4000mg /lin 40% v/v的酒精浓度)和所得结果,本方法实际实现了各种酒精浓度中甲醇的快速、简便的定量测定,准确度和精密度适宜。然而,这方面的结论性结论需要对酒精饮料的实际样品进行进一步检查。但是,据我们所知,没有任何关于这种简单方法的报道。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Introducing a New Kit based on Modified Chromotropic Acid Method for Easy Determination of Methanol
Methyl alcohol poisoning usually happens by use of contaminated ethanol. So, development of an easy and cost-effective method to determine methanol in these products can be helpful to diagnosemethanolintoxication. The aim of this paper is introducing a new kit based on chromotropic acid method for measuring the methanol content of alcoholic beverages. In this study, a new modified chromotropic acid method (as a kit) was used to determine of methanol in 700 self-made samples with diverse ethanol concentration prepared by "add found" technique. Briefly, in the proposed method, produced formaldehyde by methanol oxidation is reacted with chromotropic acid in a high acidic media. The quantification limit of this kit lies below the permitted dose and safe amount of methanol in the beverages regulated by the European Parliament and the Council. The attained results indicate Limit of Quantification of the method is1250 mg/Land all examined samples with more methanol amounts are easily determined with good accuracy and precision. As for the European standard about permitted dose of methanol in beverages (up to 4000 mg/lin 40% v/v of alcohol strength) and gained results, it seems, this proposed method practically enables rapid and easy quantitative determination of methanol in all kind of alcoholic strength with suitable accuracy and precision. However, conclusive conclusions in this area will require further examination in actual samples of alcoholic beverages. But, to the best of our knowledge, there isn’t any report about such easy method.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信