普瑞巴林作为睡眠药物的滥用:案例报告

Basavaraja Papanna, C. Lazzari, Kapil S. Kulkarni, Sivasankar Perumal
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引用次数: 1

摘要

背景:普瑞巴林是一种众所周知的抗焦虑、镇痛和抗癫痫药物。当它开始被患者用作催眠剂时,精神卫生服务部门感到震惊。方法:我们报告两例社区精神卫生小组开始滥用处方普瑞巴林的病例。在社区和住院部密切观察他们的药物滥用模式、程度和依赖标准。结果:停用普瑞巴林后,两例患者均出现以耐受、渴望为表现的依赖综合征,并出现戒断症状。他们需要替代药物来控制戒断症状。结论:普瑞巴林具有较强的成瘾性,因其催眠或诱导睡眠的特性而被滥用。依赖的发展和戒断症状的性质因人而异;然而,半衰期长的苯二氮卓类药物对普瑞巴林戒断症状有很好的治疗潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Pregabalin abuse as a sleep medication: case reports
Background: Pregabalin is well known as an anxiolytic, analgesic and antiepileptic medication. It was alarming for mental health service when it started being used as addictive agent by patients for its hypnotic properties. Methods: We report two cases from Community Mental Health Team who started abusing their prescribed Pregabalin. They were closely observed in community and on inpatient unit for their pattern and extent of drug abuse and dependence criteria. Results: Both the patients developed dependence syndrome indicated by tolerance, craving and presented with withdrawal symptoms on stopping Pregabalin. They needed replacement medication to manage withdrawal symptoms. Conclusion: Pregabalin has strong addictive potential and mostly abused by people for its hypnotic or sleep-inducing properties. The development of dependence and nature of withdrawal symptoms vary from person to person; however, Benzodiazepines with long half-life have good potential to manage Pregabalin withdrawal symptoms.
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