白芷化学性质、抗氧化活性、-淀粉酶和乙酰胆碱酯酶抑制潜力

IF 0.7 4区 医学 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE
Antonaeta Trendafilova, G. Ozek, Suleyman Yurb, F. Goger, T. Ozek, M. Rangelov, M. Todorova, I. Aneva
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引用次数: 0

摘要

特有植物白芷果实、叶、根挥发油的GC-FID/MS对比研究揭示了它们化学成分的显著差异。测定了果油中主要成分(+)-β-茶树烯的对映体纯度。此外,从果实己烷提取物中分离得到了欧前胡素、异欧前胡素、氧化去氧辛青素、水合氧化去氧辛青素、angelylpangelin和伞形草烯素。采用高效液相色谱法进一步测定了不同植物部位己烷提取物中这些香豆素的含量。研究了精油和己烷提取物的抗氧化能力和对-淀粉酶和乙酰胆碱酯酶的抑制作用。果叶精油(> 80%)和己烷提取物(> 62%)显著抑制乙酰胆碱酯酶。对叶提取物(Inh. 95.0±2.2%)和根提取物(Inh. 66.0±2.4%)的自由基清除能力进行了区分。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Chemical characterization, antioxidant activity, -amylase and acetylcholinesterase inhibitory potential of Angelica pancicii Vandas ex Velen
Comparative study GC-FID/MS of essential oils of fruits, leaves and roots of the endemic plant Angelica panciciiVandas ex Velen. revealed a significant difference in their chemical composition. The enantiomeric purity of the main component in the fruit oil (+)-β-phellandrene was also confirmed. In addition, imperatorin, isoimperatorin, oxypeucedanin, oxypeucedanin hydrate, angeloylpangelin and umbelliprenin were isolated from the fruit hexane extract. The content of these coumarins in the hexane extracts from different plant parts was further determined by HPLC. The essential oils and hexane extracts were assessed for their antioxidant potential and inhibitory effect towards -amylase and acetylcholinesterase enzymes. The fruit and leaf essential oils (> 80%) as well as the fruit hexane extract (> 62%) significantly inhibited acetylcholinesterase enzyme. Distinguish free radical scavenging properties were detected for the leaf (Inh. 95.0 ± 2.2 %) and the root (Inh. 66.0 ± 2.4 %) extracts.
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来源期刊
CiteScore
1.30
自引率
14.30%
发文量
49
审稿时长
6-12 weeks
期刊介绍: The Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas (BLACPMA), [Latin American and Caribbean Bulletin of Medicinal and Aromatic Plants]; currently edited by the publishing house MS-Editions, is a bi-monthly international publication that publishes original peerreviewed research in the field of medicinal and aromatic plants, with nearly 20 years of experience. BLACPMA is a scientific journal that publishes two types of articles: Reviews (only in English) and Original Articles (Spanish or English), its main lines of action being agronomy, anthropology and ethnobotany, industrial applications, botany, quality and standardization, ecology and biodiversity, pharmacology, phytochemistry, pharmacognosy, regulatory and legislative aspects. While all areas of medicinal plants are welcome and the experimental approaches used can be broad and interdisciplinary; other areas of research that are not mentioned depend on the Editorial Committee for their acceptance.
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