0.1%二氧化氯漱口水对口腔异味的效果评价-一项初步研究

Prajakta Brahmankar, Shweta S. Hugar, Vinayak Kumbhojkar, Neelamma Shetti
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引用次数: 0

摘要

背景:口腔异味,也被称为口臭或口臭,可以定义为从口腔中出现的一种令人反感的气味,并且很容易被他人发现。口臭的病因是多因素的,可包括几种口内和口外因素,如牙龈炎、牙周炎、慢性鼻窦炎、鼻炎、糖尿病、肺癌、肝功能不全、肝硬化、尿毒症、三甲胺尿症和鼻后滴涕。与亚氯酸盐阴离子相结合的二氧化氯导致半胱氨酸和蛋氨酸等氨基酸的氧化消耗,这些氨基酸是挥发性硫化合物(VSC)的前体。因此,它可以降低VSCs的浓度,这有助于减少口腔异味。由于证明该二氧化氯配方有效性的文献较少,因此本研究旨在评估市售含二氧化氯漱口水FRESHCLOR对患者口腔异味的抑制作用。材料和方法:本研究是在Belagavi KAHER'S VK牙科科学研究所牙周病门诊以口臭和牙龈出血为主诉的患者中进行的。根据纳入标准选取患者,分为试验组和对照组。洗牙后新鲜漱口水分发给所有试验组参与者。在基线和2周时记录各组口臭的感官评分、牙龈指数(Loe H和Silness J, 1963)和菌斑指数(Loe H和Silness J, 1964)。结果:试验组患者在2周内的口臭和牙龈及菌斑指数均较基线有统计学意义的减少。结论:含二氧化氯清新漱口水对口臭有较好的治疗效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluation of efficacy of 0.1% of chlorine dioxide mouthwash against oral malodor – A pilot study
BACKGROUND: Oral malodor, also known as halitosis or bad breath can be defined as an offensive odor that emerges from the oral cavity and can be easily detected by others. The etiology of halitosis is multifactorial and can include several intra- and extraoral factors such as gingivitis, periodontitis, chronic sinusitis, nasal inflammation, diabetes mellitus, lung carcinoma, liver insufficiency, cirrhosis, uremia, trimethylaminuria, and postnasal drip. Chlorine dioxide associated with chlorite anion results in the oxidative consumption of amino acids such as cysteine and methionine, which are precursors of volatile sulfur compounds (VSC). Thus, it can reduce the concentrations of VSCs which help in the reduction of oral malodor. Due to the lesser availability of literature to prove the effectiveness of this chlorine dioxide formula, this study is conducted to evaluate the inhibiting effect of commercially available chlorine dioxide-containing mouthwash – FRESHCLOR to combat oral malodor in patients. MATERIALS AND METHODS: The study was conducted among the patients reporting at the outpatient department of periodontics who visited with the chief complaint of bad breath and bleeding gums at KAHER'S VK Institute of Dental Sciences, Belagavi. Patients were selected according to inclusion criteria and divided into test and control groups. Post scaling Freshclor mouthwash was distributed to all test group participants. The organoleptic ratings for halitosis, gingival index (given by Loe H and Silness J, 1963), and plaque index (given by Loe H and Silness J, 1964) were recorded at baseline and 2 weeks for the group. RESULTS: There was a statistically significant reduction in halitosis with a reduction of gingival and plaque indices at 2 weeks from baseline in the test group. CONCLUSION: With the results, it can be concluded that chlorine dioxide-containing mouthwash – freshclor is effective in reducing halitosis.
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