{"title":"“纳米追踪器”用于优越的早期疾病诊断","authors":"Hanwen Wang, Jiahuan He, Guojun Chen","doi":"10.1002/mba2.12","DOIUrl":null,"url":null,"abstract":"<p>Pu and coworkers developed a disease biomarker-activatable polyfluorophore nanosensor that comprises protease-reactive peptide brushes, self-immolative linkers, and renal clearance/tumor-targeting moiety-conjugated fluorophore units, for noninvasive near-infrared fluorescence imaging and urinalysis, enabling superior early disease diagnosis.\n\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure></p>","PeriodicalId":100901,"journal":{"name":"MedComm – Biomaterials and Applications","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mba2.12","citationCount":"0","resultStr":"{\"title\":\"“Nanotracker” for superior early disease diagnosis\",\"authors\":\"Hanwen Wang, Jiahuan He, Guojun Chen\",\"doi\":\"10.1002/mba2.12\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Pu and coworkers developed a disease biomarker-activatable polyfluorophore nanosensor that comprises protease-reactive peptide brushes, self-immolative linkers, and renal clearance/tumor-targeting moiety-conjugated fluorophore units, for noninvasive near-infrared fluorescence imaging and urinalysis, enabling superior early disease diagnosis.\\n\\n <figure>\\n <div><picture>\\n <source></source></picture><p></p>\\n </div>\\n </figure></p>\",\"PeriodicalId\":100901,\"journal\":{\"name\":\"MedComm – Biomaterials and Applications\",\"volume\":\"1 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-08-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mba2.12\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"MedComm – Biomaterials and Applications\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/mba2.12\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"MedComm – Biomaterials and Applications","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/mba2.12","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
“Nanotracker” for superior early disease diagnosis
Pu and coworkers developed a disease biomarker-activatable polyfluorophore nanosensor that comprises protease-reactive peptide brushes, self-immolative linkers, and renal clearance/tumor-targeting moiety-conjugated fluorophore units, for noninvasive near-infrared fluorescence imaging and urinalysis, enabling superior early disease diagnosis.
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