EFFECT OF ALOE VERA AND CINNAMOMUM TAMALA ON BODY WEIGHT AND FEED INTAKE OF INDUCED DIABETIC MICE

Intraperitoneal injection of alloxanmonohydrate (200mg/kg)was used to inducediabetes in mice, with blood glucose levels(fasting) morethan 150mg/dl. Sixty nine mice were dividedinto 4 groups, Group I was non diabetic (normal). Group II was diabetic, Group III was the diabeticand treated with Cinnamomumtamala and group IV was diabetic and Aloe vera treated. There was noincrease in the blood glucoseat random and fasting in group Iwhereas, group II showed an increase inblood sugar level (91.00±2.65mg/dl to 250.00±3.79mg/dl) post 21 days. Cinnamomumtamala(50mg/kg) and Aloe vera (400mg/kg) appeared effective in reducing the blood sugar levels after 21days treatment. There was an increase in intake of feed and drop in body weight of group II comparedto group I. Cinnamomumtamala (50mg/kg) and Aloe vera (400mg/kg) was found effective regardingdecrease in feed intake. Increase in weight of mice occurred treated with Cinnamomumtamala(50mg/kg) and Aloe vera (400mg/kg)as compared to diabetic mice. Cinnamomumtamala and Aloevera were potentially efficient to treat hyperglycemia at recommended oral doses of 50 mg/kg and400mg/kg of body weight respectively.