低温辉光放电改性聚合物义齿对人口腔黏膜的影响

Q1 Medicine
T. Vasilieva , Aung Myat Hein , A. Vargin , E. Kudasova , E. Kochurova , M. Nekludova
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引用次数: 7

摘要

目的研究热固化聚甲基丙烯酸甲酯(PMMA)义齿基托“Villacryl H Plus”在射频放电等离子体中的改性。方法对PMMA进行非低温低压氧射频放电(13.56 MHz)修饰。结果经等离子体化学修饰的PMMA板材的水接触角比未修饰的降低了1.5 ~ 2.5倍,而其表面自由能(SFE)提高了1.5倍,这是由于等离子体修饰的PMMA表面形成了额外的含氧极性化学基团。虽然观察到改性PMMA的老化效应,但至少在7 d后,其润湿性仍高于原PMMA。该技术已成功应用于可摘PMMA义齿的改良,用于临床治疗口腔黏膜癌患者的口腔矫形康复。使用非改良义齿时,患者抱怨不适和食物咀嚼问题,并在患者脸颊形成增厚的红色扁平口腔苔藓。使用血浆改良义齿1周后,地衣结节及相关炎症完全消退。血浆改良义齿术后6个月内,患者口腔黏膜未见病变及肿瘤。结论等离子体改性可提高聚合物的SFE和润湿性,改善其与口腔组织的粘附性。生物相容性亲水性义齿表面与未改性义齿表面相比,具有较低的刺激作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

The effect of polymeric denture modified in low-temperature glow discharge on human oral mucosa: Clinical case

The effect of polymeric denture modified in low-temperature glow discharge on human oral mucosa: Clinical case

Purpose

The modification hot curing poly(methyl methacrylate) (PMMA) denturebase “Villacryl H Plus” in RF-discharge plasma is described.

Methods

The PMMA was modified in the non-temperature low-pressure oxygen RF-discharge (13.56 MHz).

Results

The plasma chemical modification of PMMA plates decreased the water contact angles by 1.5-2.5 times with respect to unmodified samples while their surface free energy (SFE) increased up to 1.5 times due to the formation of additional oxygen containing polar chemical groups at the plasma-modified PMMA surfaces. Although the ageing effect of modified PMMA was observed, its wettability was still higher than that of the original PMMA at least after 7-day storage. The technique has been successfully applied for the modification of removable PMMA denture, which was used in clinical practice for oral orthopedic rehabilitation of a patient after the treatment of buccal mucosa cancer. Whenusing the non-modified denture the patient complained of discomfort and food chewing problems and the hypertrophic red flat oral lichen formed at the patient’s cheek. The full regression of lichennodules and associated inflammation was observed after the usage of the plasma modified denture for one week. Within six-month ware of the plasma modified denture no pathological elements or neoplasms were found on the patients’ oral mucosa.

Conclusion

Plasma modification of the dentures made of hot curing PMMAincreases the SFE and wettability of the polymer and improves its adhesion to oral tissues. The biocompatible hydrophilic denture surface has less irritating effect in comparison with the non-modified one, as the positive clinical dynamics showed.

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来源期刊
Clinical Plasma Medicine
Clinical Plasma Medicine MEDICINE, RESEARCH & EXPERIMENTAL-
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