Exercise-Induced Bronchoconstriction in Children and Adolescents:

Exercise-induced bronchoconstriction (EIB) is common in children. This article reviews the epidemiology, clinical presentation, pathophysiology, diagnosis, and treatment of EIB. EIB is caused by transient narrowing of the airways during or most often after exercise and indicates airway hyperresponsiveness. EIB is an important cause of exercise limitation in children. However, the diagnosis of EIB can be challenging because symptoms poorly predict the presence of EIB. Bronchial challenges, such as cardiopulmonary exercise testing, are required to document EIB. The severity of EIB is worsened by exposure to inhalational toxicants such as chlorine in pools and air pollution. In most children, EIB can be effectively prevented by both nonpharmacological means and medications. Educating the child, his/her family, and supervising adults about asthma triggers and management is important. Prompt recognition and treatment of an asthma attack associated with exercise is critical; bronchodilators should be on the sid...