THE EFFECT OF QUR’AN RECITATION ON BEHAVIOR AND HISTOLOGY OF GLIA CELLS IN DEPRESSED MICE (MUS MUSCULUS BALB/C)

Background: Depression in mice (Mus musculus Balb/c) is characterized by decreased cognitive function of mice because there is damage in mice’s hippocampus, especially in ammonic horn. Qur’an recitation has effect as antidepressants. The purpose of this study was to find out the effect of Qur’an recitation on behavior and glia cells in depressed mice. Methods: this study was a true experimental research with post-test control group design. The design of this study used five groups, consisting of one negative control group, one positive control group and three treatment groups with Qur’an recitation therapy 1x1 hours, 2x1 hours and 2x2 hours (one week). Results: The spatial memory behavior of mice in the control group [+] was longer, namely 77.936 when compared to other groups. The hanging time behavior of mice increased in the control [+], P[1], P[2] and P[3] groups. Histology of mice’s glia cells decreased in the control [+], treatment [1], treatment [2] and treatment [3] groups. Qur’an recitation therapy on P[1] and P[2] affected the histology of the number of glia cells in depressed mice model, so that no glia cells were damaged (p<0.05). Conclusion: Qur’an recitation therapy had no effect on the hanging time behavior of mice, but it did affect the spatial memory behavior of mice in group P[1] and histology of mice’s glia cells in groups P[1] and P[3].