以吲哚-1,3-二酮为核的查尔酮类吡唑啉衍生物的合成、表征及其抗菌和抗结核活性

Siddharth Desai, V. G. Sastry, A. Malpani, Kishore Singh
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引用次数: 0

摘要

DOI链接:http://dx.doi.org/10.21276/IJRDPL。2278.0238.2017;摘要:以茚-1,3-二酮的查尔酮为原料合成了一系列苯基吡唑啉衍生物。取代查尔酮已被合成并有报道。以吲哚-1,3-二酮查尔酮与苯基肼为原料,在碱性介质中乙醇存在下缩合合成了苯基吡唑啉衍生物。新合成的化合物(7a-f)通过IR、H-NMR和TLC进行了表征。新化合物已被评价其抗菌、抗真菌和抗结核活性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Synthesis, characterization, antimicrobial and antitubercular activity of Some Pyrazoline derivatives from Chalcones bearing indane-1,3-dione as nucleus
DOI Link: http://dx.doi.org/10.21276/IJRDPL. 2278.0238.2017; 6(2): 2530-2534 Abstract: A series of phenyl pyrazoline derivatives have been synthesized from chalcones of indane-1,3-dione. The substituted chalcones have already been synthesized and reported by us. The phenyl pyrazoline derivatives were synthesized by condensation of chalcone of indane-1,3-dione with phenyl hydrazine in basic medium in the presence of ethanol. The newly synthesized compounds (7a-f) have been characterized by IR and H-NMR Spectroscopy and TLC. The new compounds have been evaluated for their antibacterial, antifungal and antitubercular activities.
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