GeneXpert MTB/RIF在结核病检测中的价值:基于文献计量学的分析与综述

IF 2.3 3区化学 Q3 CHEMISTRY, ANALYTICAL

Journal of Analytical Methods in Chemistry Pub Date : 2022-10-15 DOI:10.1155/2022/2915018

Zhiyi Li

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引用次数: 2

摘要

随着医学科学技术的不断发展，特别是精准诊疗时代的到来，分子生物学检测技术作为结核病早期诊断的辅助手段受到广泛重视和应用。GeneXpert结核分枝杆菌(MTB)技术是由造父变星公司开发的一套半嵌套实时荧光定量PCR体外诊断技术。它以利福平耐药基因rpoB为靶点，可在2 h内检测出MTB和利福平耐药。本文利用文献计量学软件CiteSpace和Bibliometrix对GeneXpert相关文献进行分析。从2011年到2021年，共分析了151篇文章。这篇基于文献计量学的综述总结了GeneXpert在结核病诊断中的发展历史及其现状。采用不同国家对该主题的贡献、期刊分析、关键论文分析、关键词聚类等方法对该主题进行分析。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The Value of GeneXpert MTB/RIF for Detection in Tuberculosis: A Bibliometrics-Based Analysis and Review

With the continuous development of medical science and technology, especially with the advent of the era of precision diagnosis and treatment, molecular biology detection technology is widely valued and applied as an aid to early diagnosis of tuberculosis. The GeneXpert Mycobacterium tuberculosis Branching (MTB) technology is a suite of semi-nested real-time fluorescent quantitative PCR in vitro diagnostic technologies developed by Cepheid Inc. It targets the rifampicin resistance gene, rpoB, and can detect both MTB and resistance to rifampicin within 2 h. This review analyzed the papers related to GeneXpert using bibliometric software CiteSpace and Bibliometrix. A total of 151 articles were analyzed, spanning from 2011 to 2021. This bibliometrics-based review summarizes the history of the development of GeneXpert in tuberculosis diagnosis and its current status. Contributions of different countries to the topic, journal analysis, key paper analysis, and clustering of keywords were used to analyze this topic.

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来源期刊

Journal of Analytical Methods in Chemistry CHEMISTRY, ANALYTICAL-ENGINEERING, CIVIL

CiteScore

4.80

自引率

3.80%

发文量

审稿时长

6-12 weeks

期刊介绍： Journal of Analytical Methods in Chemistry publishes papers reporting methods and instrumentation for chemical analysis, and their application to real-world problems. Articles may be either practical or theoretical. Subject areas include (but are by no means limited to): Separation Spectroscopy Mass spectrometry Chromatography Analytical Sample Preparation Electrochemical analysis Hyphenated techniques Data processing As well as original research, Journal of Analytical Methods in Chemistry also publishes focused review articles that examine the state of the art, identify emerging trends, and suggest future directions for developing fields.