结肠镜检查增加无梗锯齿状息肉的检出率

IF 1.8 4区医学 Q3 PATHOLOGY

International Journal of Experimental Pathology Pub Date : 2021-12-29 DOI:10.33696/pathology.2.030

A. Fraser

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引用次数: 0

摘要

结肠镜检查中所有腺瘤的发现和切除与间隔期癌发生率降低相关[1,2]。这与结直肠癌的腺瘤-癌序列一致。锯齿状息肉癌途径的发现强调了检测和切除无梗锯齿状息肉的重要性。锯齿状息肉是结直肠癌的前体病变，占结直肠癌的15%至30%。它们被过多地认为是间隔期癌症的原因[3]。在瑞典的一项前瞻性记录关联研究中，锯齿状息肉的检测与结直肠癌的风险明显相关，其与管状腺瘤的风险相似(无柄锯齿状息肉的风险比为1.77(1.34 - 1.34)，管状腺瘤的风险比为1.41(1.30 - 1.52))[4]。

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Colonoscopy Audit Increases Detection of Sessile Serrated Polyps

Detection and removal of all adenomas at colonoscopy is associated with a reduced interval cancer rate [1,2]. This is consistent with the adenoma-carcinoma sequence for colorectal cancer. The identification of the serrated polyp cancer pathway has emphasized the importance of detection and removal of sessile serrated polyps. Serrated polyps are precursor lesions ac counting for 15% to 30% of colorectal cancers. They are overrepresented as a cause of interval cancers [3]. The detection of serrated polyps has been clearly linked to the risk of colorectal cancer in a prospective record linkage study in Sweden with a similar risk to tubular adenomas (HR of 1·77 (1·34-2·34) for sessile serrated polyps and 1·41 (1·30-1·52) for tubular adenomas) [4].

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来源期刊

International Journal of Experimental Pathology 医学-病理学

CiteScore

4.50

自引率

3.30%

发文量

审稿时长

>12 weeks

期刊介绍： Experimental Pathology encompasses the use of multidisciplinary scientific techniques to investigate the pathogenesis and progression of pathologic processes. The International Journal of Experimental Pathology - IJEP - publishes papers which afford new and imaginative insights into the basic mechanisms underlying human disease, including in vitro work, animal models, and clinical research. Aiming to report on work that addresses the common theme of mechanism at a cellular and molecular level, IJEP publishes both original experimental investigations and review articles. Recent themes for review series have covered topics as diverse as "Viruses and Cancer", "Granulomatous Diseases", "Stem cells" and "Cardiovascular Pathology".