膀胱切除术后尿改道的并发症及生活质量

Elmar W. Gerharz , Alexander Roosen , Wiking Månsson
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引用次数: 18

摘要

目的:本综述的目的是概述根治性膀胱切除术患者尿改道后的特定手术并发症,代谢后果和生活质量(QOL)。方法:在综合文献检索(MEDLINE)的基础上,以当代膀胱切除术系列为重点,对已发表的尿分流知识进行分析。结果:尽管事实上,尿分流在当今很常见,现有文献也相当广泛,但绝大多数假设都是基于低水平的证据(回顾性、单机构病例系列、小样本量和短期随访)。在这个领域很少有随机试验。根治性膀胱切除术后的早期和晚期手术并发症在过去三十年中因失禁和膀胱转移而减少,但仍然很重要。虽然代谢紊乱是常见的后大陆形式的尿分流,问题可以最小化在大多数情况下。大多数报告证明,膀胱切除术后的生活质量很高,与尿转移类型无关,尽管泌尿和性问题很常见。结论:谨慎的患者选择,严格遵守正确的手术技术和适当的终身随访是成功治疗膀胱癌根治性膀胱切除术患者的关键。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Complications and Quality of Life Following Urinary Diversion After Cystectomy

Objective:

The aim of this review is to outline specific surgical complications, metabolic consequences and quality of life (QOL) following urinary diversion in patients undergoing radical cystectomy.

Methods:

Based on a comprehensive literature search (MEDLINE) the published knowledge on urinary diversion was examined regarding the research question with an emphasis on contemporary cystectomy series.

Results:

Despite the fact, that urinary diversion is commonplace in these days and the existing literature is rather extensive, the vast majority of assumptions are based on low level evidence (retrospective, single-institutional case series with small sample sizes and short-term followup). There are few randomized trials in this field.

Early and late surgical complications following radical cystectomy have decreased over the past three decades for both incontinent and continent diversion, but are still significant. While metabolic disturbances are common after continent forms of urinary diversion, the problems can be minimized in most cases. Most reports testify that QOL is high after cystectomy irrespective of type of urinary diversion although urinary and sexual problems are common.

Conclusion:

Careful patient selection, strict adherence to proper surgical technique and appropriate life-long follow-up are of paramount importance in the successful management of patients undergoing radical cystectomy for bladder cancer.

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