纳米氧化石墨烯加入聚甲基丙烯酸甲酯抗菌效果和热膨胀。

R. Gamal, Y. Gomaa, A. M. Said
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引用次数: 9

摘要

目的:研究不同浓度纳米氧化石墨烯(GO)对市售聚甲基丙烯酸甲酯(PMMA)的抑菌效果和热膨胀性能。方法:将重量为0%、0.05%、0.1%、0.15%和1%的纳米氧化石墨烯分别掺入PMMA中形成I-V基团。为评价其对变形链球菌的抑菌效果,对氧化石墨烯分散体进行最低抑菌浓度(MIC)测定,并对I-IV组进行琼脂孔扩散试验。通过测量热膨胀线性系数来评价热膨胀。结果:MIC各浓度的抑菌作用范围在0.5 ~ 2mm之间。琼脂孔扩散法评价各组除ⅱ组外均无抑菌区。随着氧化石墨烯浓度的增加,热膨胀系数显著降低。结论:在PMMA中掺入0.5%浓度的氧化石墨烯可抑制变形链球菌的生长。氧化石墨烯的浓度与热膨胀系数呈反比关系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Incorporating nano graphene oxide to poly-methyl methacrylate; antibacterial effect and thermal expansion.
Aim: This in vitro study was performed to evaluate antibacterial effect and thermal expansion of commercial available poly-methyl methacrylate (PMMA) incorporated by nano graphene oxide (GO) in different concentration. Method: Nano graphene oxide in five concentrations 0%, 0.05%, 0.1%, 0.15% and 1% by weight was incorporated to PMMA to form groups I-V respectively. To evaluate the antibacterial effect against Streptococcus Mutans, minimal inhibitory concentration (MIC) for GO dispersion was done and agar well diffusion test for groups I-IV was done. Thermal expansion was assessed through measuring the linear coefficient of thermal expansion. Results: For antibacterial effect, all concentrations tested for MIC showed inhibition zone varied from 0.5 to 2mm in diameter. All tested groups evaluated by agar well diffusion method showed no inhibition zones except for group II. Significant reduction in coefficient of thermal expansion was showed by increasing GO concentration. Conclusions: Incorporation of GO in to PMMA at concentration of 0.5% can inhibit the growth of Streptococcus Mutans. There is an inverse relation between the concentrations of GO and the coefficient of thermal expansion.
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