{"title":"聚乙烯醇浸泡时间变化对细菌-水解纤维素候选支架生物复合材料特性的影响","authors":"L. Indrio","doi":"10.20473/JSCRTE.V2I2.11893","DOIUrl":null,"url":null,"abstract":"Bone defects due to trauma, tumors, congenital abnormalities, degeneration and other diseases are still major problems in the field of orthopedics and traumatology. Based on data in Asia, Indonesia is the country with the highest number of fracture sufferers, there are as many as 300-400 cases of bone surgery per month in hospitals. Dr. Soetomo Surabaya (Gunawarman et al, 2010). Repair of damaged bones can be overcome with material that can accelerate the process of bone healing (bone healing). This research was conducted to synthesize hydroxyaparite bacterial cellulose scaffold as a candidate for bone healing. Bacterial cellulose as a matrix was synthesized by culturing Acetobacter xylnum, while hydroxyapatite as filler was synthesized by immersion into a solution of CaCl2 and Na2HPO4, the scaffold formation process using freeze dried method. Composite formation was varied by immersion in Polyvynil pirrolidone (PVP) for 0, 1, 2, 3, 4 days. Furthermore, samples were characterized using FTIR-Spectroscopy showing the presence of carbonates containing apatite crystals in all five samples.","PeriodicalId":17049,"journal":{"name":"Journal of Stem Cell Research and Tissue Engineering","volume":"79 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Effect Of Immersion Time Variation in Polyvynyl Piprolidone Against Characteristics Of Scaffold Biocomposit Of Bacterial-Hydrocysiatatic Cellulose as Candidate\",\"authors\":\"L. Indrio\",\"doi\":\"10.20473/JSCRTE.V2I2.11893\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Bone defects due to trauma, tumors, congenital abnormalities, degeneration and other diseases are still major problems in the field of orthopedics and traumatology. Based on data in Asia, Indonesia is the country with the highest number of fracture sufferers, there are as many as 300-400 cases of bone surgery per month in hospitals. Dr. Soetomo Surabaya (Gunawarman et al, 2010). Repair of damaged bones can be overcome with material that can accelerate the process of bone healing (bone healing). This research was conducted to synthesize hydroxyaparite bacterial cellulose scaffold as a candidate for bone healing. Bacterial cellulose as a matrix was synthesized by culturing Acetobacter xylnum, while hydroxyapatite as filler was synthesized by immersion into a solution of CaCl2 and Na2HPO4, the scaffold formation process using freeze dried method. Composite formation was varied by immersion in Polyvynil pirrolidone (PVP) for 0, 1, 2, 3, 4 days. Furthermore, samples were characterized using FTIR-Spectroscopy showing the presence of carbonates containing apatite crystals in all five samples.\",\"PeriodicalId\":17049,\"journal\":{\"name\":\"Journal of Stem Cell Research and Tissue Engineering\",\"volume\":\"79 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-02-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Stem Cell Research and Tissue Engineering\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.20473/JSCRTE.V2I2.11893\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Stem Cell Research and Tissue Engineering","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.20473/JSCRTE.V2I2.11893","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
创伤、肿瘤、先天性畸形、退行性变等疾病引起的骨缺损仍然是骨科和创伤学领域的主要问题。根据亚洲的数据,印度尼西亚是骨折患者人数最多的国家,医院每月有多达300-400例骨手术。Soetomo Surabaya博士(Gunawarman et al, 2010)。受损骨骼的修复可以用加速骨愈合过程的材料来克服。本研究旨在合成羟基磷灰石细菌纤维素支架作为骨愈合的候选材料。以细菌纤维素为基质,通过培养木醋杆菌合成,以羟基磷灰石为填料,在CaCl2和Na2HPO4溶液中浸泡合成,支架的形成过程采用冻干法。在聚乙烯吡咯烷酮(PVP)中浸泡0、1、2、3、4天后,复合物质的形成发生了变化。此外,使用红外光谱对样品进行了表征,显示在所有五个样品中都存在含有磷灰石晶体的碳酸盐。
The Effect Of Immersion Time Variation in Polyvynyl Piprolidone Against Characteristics Of Scaffold Biocomposit Of Bacterial-Hydrocysiatatic Cellulose as Candidate
Bone defects due to trauma, tumors, congenital abnormalities, degeneration and other diseases are still major problems in the field of orthopedics and traumatology. Based on data in Asia, Indonesia is the country with the highest number of fracture sufferers, there are as many as 300-400 cases of bone surgery per month in hospitals. Dr. Soetomo Surabaya (Gunawarman et al, 2010). Repair of damaged bones can be overcome with material that can accelerate the process of bone healing (bone healing). This research was conducted to synthesize hydroxyaparite bacterial cellulose scaffold as a candidate for bone healing. Bacterial cellulose as a matrix was synthesized by culturing Acetobacter xylnum, while hydroxyapatite as filler was synthesized by immersion into a solution of CaCl2 and Na2HPO4, the scaffold formation process using freeze dried method. Composite formation was varied by immersion in Polyvynil pirrolidone (PVP) for 0, 1, 2, 3, 4 days. Furthermore, samples were characterized using FTIR-Spectroscopy showing the presence of carbonates containing apatite crystals in all five samples.