高入射通量和长脉冲激光照射结合冷冻剂喷雾冷却:离体研究

中国地球物理学会年刊 Pub Date : 2002-12-01 DOI:10.1109/IEMBS.2002.1053277

T. Dai, J. Tunnell, B. Pikkula, D. Chang, B. Anvari

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引用次数: 0

摘要

我们研究了高入射能量，长脉冲激光照射结合冷冻剂喷雾冷却(CSC)在离体人体皮肤上的应用。从接受经直肌肌皮瓣手术的患者中获得不同类型的腹部皮肤样本(Fitzpatrick I-VI型)。每种皮肤类型均接受Candela Vbeam/spl trade/ laser(波长/spl λ /=595 nm)照射，照射剂量分别为D/sub /spl theta//=6、10、15、20 J/cm/sup 2/，脉冲持续时间/spl tau//sub laser/=1.5、10、40 ms，无CSC和有CSC。初步结果表明，浅色皮肤比目前在治疗环境中使用的皮肤能承受更高的事件影响水平。在激光脉冲入射剂量相同的情况下，较长的脉冲持续时间可以降低表皮热损伤程度。

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High incident fluence and long pulse laser irradiation in conjunction with cryogen spray cooling: an ex-vivo study

We have investigated the utilization of high incident fluence, long pulse laser irradiation in conjunction with cryogen spray cooling (CSC) on ex-vivo human skin. Abdominal skin samples of different types (Fitzpatrick type I-VI) were obtained from patients undergoing the trans-rectus myocutaneous flap procedures. Each skin type was irradiated with a Candela Vbeam/spl trade/ laser (wavelength /spl lambda/=595 nm) at incident dosages of D/sub /spl theta//=6, 10, 15, 20 J/cm/sup 2/, pulse durations of /spl tau//sub laser/=1.5, 10, 40 ms, without and with CSC. Preliminary results indicate that lightly pigmented skins can sustain higher incident fluence levels than those currently used in therapeutic settings. While the incident dosage of the laser pulse remains the same, longer pulse duration can decrease the degree of epidermal thermal injury.

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来源期刊

中国地球物理学会年刊

自引率

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368