新型冠状病毒SARS-CoV-2 (2019-nCoV)的生物学特性

E. Abdu, A. Mariamenatu
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引用次数: 0

摘要

新型冠状病毒(2019 - nCoV)是一种正义RNA病毒,具有编码刺突(S)、膜(M)、核衣壳(N)和包膜(E)蛋白的四个基因。该病毒起源于销售活体动物的海鲜市场,是2019年冠状病毒病(COVID - 19)的罪魁祸首。最初的病例可追溯到中国湖北省武汉市,报告为一种新兴的呼吸道病毒,疫情于2019年12月31日向世卫组织报告,并很快确定病原为乙型冠状病毒,命名为严重急性呼吸系统综合征冠状病毒2 (SARS - CoV - 2);这是一种高度传染性的病毒,3月份在中国境外迅速传播,世界卫生组织不得不于2020年3月11日宣布COVID - 19大流行,截至2020年8月15日,已报告确诊病例超过2100万例,其中>全世界有755 786人死亡。今天的新型冠状病毒- 2019是传染性最强的病毒,具有高传染性和低死亡率,其中在16(60)岁以上和已有健康状况的人群中观察到高死亡率。迄今为止,还没有临床批准的抗病毒药物或疫苗可用于对抗COVID - 19。但是,已经讨论了预防措施,如口罩、手卫生习惯、避免公共接触、病例发现、接触者追踪和隔离等,以减少传播。因此,本文就新型冠状病毒2019的基本生物学特性进行综述。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Biological Property of Novel Coronavirus SARS-CoV-2 (2019-nCoV)
Novel coronavirus (2019 - nCoV) is a positive - sense RNA virus that possesses four genes that encode the spike (S), membrane (M), nucleocapsid (N), and envelope (E) proteins. The virus was originated in seafood market selling live animals and responsible for coronavirus disease 2019 (COVID - 19). The initial case was traced to the city of Wuhan in the province of Hubei, China, reported as an emerging re spiratory virus, the outbreak was reported to WHO on December 31, 2019, and soon after identified the causative pathogen as a beta coronavirus named as severe acute respiratory syndrome coronavirus 2 (SARS - CoV - 2);Furthermore, It is a highly contagious vir us that spreads swiftly outside of China in March and the World Health Organization had to declare COVID - 19 pandemic on March 11, 2020, and as of August 15, 2020, more than 21 million confirmed cases have been reported, with > 755 786 deaths worldwide. Thi s day's novel coronavirus - 2019 is the most infectious virus with high infectivity and low mortality rate where a high mortality rate was observed among people above the age of sixteen (60) years and with the pre - existing health condition. To date, there is no clinically approved antiviral drug or vaccine available to be used against COVID - 19. However, Preventive measures such as masks, hand hygiene practices, avoidance of public contact, case detection, contact tracing, and quarantines have been discussed a s ways to reduce transmission. Therefore, the purpose of this review is to summarize the basic biological properties of novel coronavirus 2019.
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