乳腺癌患者术后疼痛综合征及其相关因素的前瞻性研究

Hao Zhang, Pengcheng Ye, Yinglin Wang, Qingxiu Wang
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摘要

背景:手术通常是乳腺癌的第一种治疗方法,随之而来的是一些并发症,如慢性疼痛。乳房切除术后疼痛综合征(PMPS)是乳腺癌幸存者中常见的并发症,被认为是一种持续6个月以上的手术侧慢性神经性疼痛。乳房手术后慢性疼痛的确切机制和相关危险因素尚不清楚。本研究旨在了解中国乳腺癌患者术后疼痛综合征的流行病学特征,并分析其相关危险因素。方法:对202例择期乳房手术的女性乳腺癌患者进行为期6个月的前瞻性队列研究。采用ID自评量表评估慢性疼痛患者的疼痛发生率。对疼痛及16项相关危险因素进行统计学分析。结果:对202例接受选择性乳房手术的女性乳腺癌患者进行了为期6个月的前瞻性队列研究。采用ID自评量表评估慢性疼痛患者的疼痛发生率。对疼痛及16项相关危险因素进行统计学分析。结论:PMPS在乳腺癌术后患者中占有一定比例。年龄和心理异常与术前乳腺癌患者可能会经历PMPS。对创伤手术方式的选择、术前的心理干预以及术后急性疼痛的处理对预防PMPS的发生具有一定的意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prospective Study of Postoperative Pain Syndrome in Patients with BreastCancer and its Related Factors
Background: Surgery is usually the first treatment for breast cancer which is followed by some complications such as chronic pain. Post mastectomy pain syndrome (PMPS) is a common complication among breast cancer survivors and is considered as a chronic neuropathic pain in the side of surgery which persists more than six months. The exact mechanisms and related risk factors of the chronic pain after breast surgery are unknown. The aim of this study is to investigate the epidemiological characteristics of postoperative pain syndrome in Chinese breast cancer patients, and to analyze the related risk factors. Methods: A prospective cohort study of 202 female breast cancer patients undergoing elective breast surgery for a period of 6 months follow-up survey. The incidence rate of pain in patients with chronic pain was assessed by the self-rating scale of ID. Pain and 16 related risk factors were statistically analyzed. Results: A prospective cohort study of 202 female breast cancer patients undergoing elective breast surgery for a period of 6 months follow-up survey. The incidence rate of pain in patients with chronic pain was assessed by the self-rating scale of ID. Pain and 16 related risk factors were statistically analyzed. Conclusions: PMPS occupies a certain proportion in breast cancer patients after surgery. Age and psychological abnormalities associated with preoperative breast cancer patients may undergo PMPS. It is possible to have a certain significance to choose the operation mode of the trauma, the psychological intervention before the operation and the management of the acute pain after the operation to prevent the PMPS.
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