甲基萘醌-7:肌肉和神经健康的广泛生理相关性

D. Mehta, A. de Souza, Shashank S. Jadhav
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引用次数: 1

摘要

甲基萘醌-7在心血管和骨骼健康中起着重要作用。近年来,人们对了解甲基萘醌-7在健康和疾病中的作用越来越感兴趣。一些基于人群的研究报告了长链甲基萘醌的特定健康影响,特别是MK-7、MK-8和MK-9。有几项流行病学研究、临床试验以及体内和体外研究证实了甲基萘醌-7在健康和疾病中的作用。最近,Synergia生命科学的研究小组发现,甲基萘醌-7在能量稳态(VO2max)、周围神经病变、肌肉痉挛和线粒体呼吸方面具有更广泛的作用,不仅通过改善电子传递,而且通过灌注改善氧的可用性。在本章中,作者讨论了甲基萘醌-7更广泛的生理作用,重点介绍了甲基萘醌-7在肌肉和神经健康领域的最新研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Menaquinone-7: Wide Ranging Physiological Relevance in Muscle and Nerve Health
Menaquinone-7 plays a significant role in cardiovascular and bone health. In recent times there is a growing interest in understanding the role of Menaquinone-7 in health and diseases. Several population-based studies have reported specific health effects of the long-chain menaquinones, notably MK-7, MK-8, and MK-9. There are several epidemiological studies, clinical trials, along with in vivo and in vitro studies confirming the role of Menaquinone-7 in health and diseases. More recently, research group at Synergia Life Sciences has discovered a wider role for Menaquinone-7 in energy homeostasis (VO2max), peripheral neuropathy, muscle cramps and mitochondrial respiration not only through improvement of the electron transport but also the perfusion improving oxygen availability. In the current chapter, the authors have discussed the wider physiological role of Menaquinone-7 highlighting the recent research with Menaquinone-7 in the areas of Muscle and Nerve Health.
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