强的松对大鼠尿蛋白组和疾病生物标志物的影响

MOJ proteomics & bioinformatics Pub Date : 2017-10-06 DOI:10.15406/MOJPB.2017.06.00191

Jianqiang Wu, Xundou Li, Youhe Gao

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引用次数: 0

摘要

疾病生物标志物是与特定病理生理条件相关的可测量变化，可用于诊断和监测疾病，预测预后并反映治疗效率。尿液作为一种无创可及且相对稳定的液体，是通过蛋白质组学方法发现生物标志物的一种有前景的临床样本来源[1]。近年来，尿蛋白质组学在疾病生物标志物研究中受到越来越多的关注。

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Effects of prednisone on urinary proteome and disease biomarkers in a rat model

Disease biomarkers are measurable changes associated with specific pathophysiological conditions that can be used to diagnose and monitor diseases, to predict prognoses and to reflect treatment efficiency. As a non-invasively accessible and relatively stable liquid, urine is a promising clinical sample source for biomarker discovery via proteomics approaches [1]. Recently, urinary proteomics has received increasing attention in disease biomarker research.

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MOJ proteomics & bioinformatics

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